TY - JOUR
T1 - Green Tea Consumption and Mortality among Japanese Elderly People
T2 - The Prospective Shizuoka Elderly Cohort
AU - Suzuki, Etsuji
AU - Yorifuji, Takashi
AU - Takao, Soshi
AU - Komatsu, Hirokazu
AU - Sugiyama, Masumi
AU - Ohta, Toshiki
AU - Ishikawa-Takata, Kazuko
AU - Doi, Hiroyuki
N1 - Funding Information:
This study was funded by Health and Labour Sciences Research Grants, Comprehensive Research on Aging and Health. The authors are grateful to Ichiro Kawachi for his valuable comments on the results of the current study. We also thank Saori Kashima for her assistance with data linkage.
PY - 2009/10
Y1 - 2009/10
N2 - Purpose: To investigate the association between green tea consumption and mortality from all causes, cancer, and cardiovascular disease (CVD) among elderly people. Methods: In a population-based, prospective cohort study, a total of 14,001 elderly residents (aged 65-84 years), randomly chosen from all 74 municipalities in Shizuoka, Japan, completed questionnaires that included items about frequency of green tea consumption. They were followed for up to 6 years, from December 1999 to March 2006. Consequently, 12,251 subjects were analyzed to estimate the hazard ratios (HRs) for all-cause mortality, cancer, and CVD. Results: Among 64,002 person-years, 1,224 deaths were identified (follow-up rate, 71.6%). The multivariate HRs and 95% confidence intervals (CIs) for CVD mortality compared those who consumed seven or more cups per day with those who consumed less than one cup per day, were 0.24 (0.14-0.40), 0.30 (0.15-0.61), and 0.18 (0.08-0.40) for total participants, men, and women, respectively. Although green tea consumption was not inversely associated with cancer mortality, green tea consumption and colorectal cancer mortality were inversely associated with a moderate dose-response relationship. Conclusions: Green tea consumption is associated with reduced mortality from all causes and CVD. This study also suggests that green tea could have protective effects against colorectal cancer.
AB - Purpose: To investigate the association between green tea consumption and mortality from all causes, cancer, and cardiovascular disease (CVD) among elderly people. Methods: In a population-based, prospective cohort study, a total of 14,001 elderly residents (aged 65-84 years), randomly chosen from all 74 municipalities in Shizuoka, Japan, completed questionnaires that included items about frequency of green tea consumption. They were followed for up to 6 years, from December 1999 to March 2006. Consequently, 12,251 subjects were analyzed to estimate the hazard ratios (HRs) for all-cause mortality, cancer, and CVD. Results: Among 64,002 person-years, 1,224 deaths were identified (follow-up rate, 71.6%). The multivariate HRs and 95% confidence intervals (CIs) for CVD mortality compared those who consumed seven or more cups per day with those who consumed less than one cup per day, were 0.24 (0.14-0.40), 0.30 (0.15-0.61), and 0.18 (0.08-0.40) for total participants, men, and women, respectively. Although green tea consumption was not inversely associated with cancer mortality, green tea consumption and colorectal cancer mortality were inversely associated with a moderate dose-response relationship. Conclusions: Green tea consumption is associated with reduced mortality from all causes and CVD. This study also suggests that green tea could have protective effects against colorectal cancer.
KW - Aged
KW - Cohort Studies
KW - Japan
KW - Prospective Studies
KW - Tea
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U2 - 10.1016/j.annepidem.2009.06.003
DO - 10.1016/j.annepidem.2009.06.003
M3 - Article
C2 - 19628408
AN - SCOPUS:69449089722
SN - 1047-2797
VL - 19
SP - 732
EP - 739
JO - Annals of Epidemiology
JF - Annals of Epidemiology
IS - 10
ER -
