Heerfordt's syndrome associated with a high fever and elevation of TNF-α

Go Makimoto, Nobuaki Miyahara, Mao Yoshikawa, Akihiko Taniguchi, Arihiko Kanehiro, Mitsune Tanimoto, Katsuyuki Kiura

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Heerfordt's syndrome is a rare manifestation of sarcoidosis and is defined as a combination of facial palsy, parotid swelling, and uveitis, associated with a low-grade fever. We report a case of Heerfordt's syndrome presenting with a high fever and increased serum tumor necrosis factor alpha (TNF-α) levels. The patient had facial palsy, parotid swelling, uveitis, and swelling of the right supraclavicular and hilar lymph nodes. Corticosteroid therapy was initiated, and her symptoms soon resolved completely, in tandem with a decrease in TNF-α serum levels.

Original languageEnglish
Pages (from-to)273-278
Number of pages6
JournalActa medica Okayama
Issue number4
Publication statusPublished - 2016


  • Heerfordt's syndrome
  • Sarcoidosis
  • TNF-α

ASJC Scopus subject areas

  • General Biochemistry,Genetics and Molecular Biology


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