Heerfordt's syndrome associated with trigeminal nerve palsy and reversed halo sign

Go Makimoto, Keita Kawakado, Masamoto Nakanishi, Tomoki Tamura, Minori Noda, Satoko Makimoto, Yumiko Sato, Shoichi Kuyama

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Heerfordt's syndrome is a rare subtype of sarcoidosis and features a combination of facial palsy, parotid swelling, and uveitis, associated with a low-grade fever. Cases with two of three symptoms are called "incomplete Heerfordt's syndrome." Heerfordt's syndrome involving other cranial nerve symptoms is relatively rare. We herein report a case of incomplete Heerfordt's syndrome presenting with trigeminal nerve palsy and a reversed halo sign, a rare manifestation of pulmonary sarcoidosis. The histological diagnosis following a biopsy of the parotid gland and endobronchial ultrasound-guided trans-bronchial needle aspiration of the mediastinal lymph nodes was sarcoidosis. The symptoms and lung lesions improved after corticosteroid therapy.

Original languageEnglish
Pages (from-to)1747-1752
Number of pages6
JournalInternal Medicine
Issue number11
Publication statusPublished - Jun 1 2021
Externally publishedYes


  • Endobronchial ultrasoundguided transbronchial needle aspiration
  • Heerfordt's syndrome
  • Reversed halo sign
  • Trigeminal nerve palsy

ASJC Scopus subject areas

  • Internal Medicine


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