TY - GEN
T1 - Highly dynamic self-organizing SMG morphogenesis in 3D culture
AU - Farahat, Mahmoud
AU - Sathi, Gulsan Ara
AU - Taketa, Hiroaki
AU - Oshima, Masamitsu
AU - Kuboki, Takuo
AU - Matsumoto, Takuya
PY - 2016/3/21
Y1 - 2016/3/21
N2 - Biological tissues have specific cell patterns and well-organized structures which result from various organogenesis processes. Among which is branching morphogenesis which is the key developmental processes for many glandular tissues including lungs, kidney, salivary gland and liver. Many approaches were suggested to regenerate salivary gland tissue in vitro. Here, we developed a 3D culture technique to study and recapitulate the dynamic forces generated during SMG organogenesis by utilizing time lapse live imaging to monitor the cellular migration and reorganization process of both epithelium and mesenchyme cells.
AB - Biological tissues have specific cell patterns and well-organized structures which result from various organogenesis processes. Among which is branching morphogenesis which is the key developmental processes for many glandular tissues including lungs, kidney, salivary gland and liver. Many approaches were suggested to regenerate salivary gland tissue in vitro. Here, we developed a 3D culture technique to study and recapitulate the dynamic forces generated during SMG organogenesis by utilizing time lapse live imaging to monitor the cellular migration and reorganization process of both epithelium and mesenchyme cells.
UR - http://www.scopus.com/inward/record.url?scp=84966650482&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84966650482&partnerID=8YFLogxK
U2 - 10.1109/MHS.2015.7438259
DO - 10.1109/MHS.2015.7438259
M3 - Conference contribution
AN - SCOPUS:84966650482
T3 - 2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015
BT - 2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015
Y2 - 23 November 2015 through 25 November 2015
ER -