Hilar cholangiocarcinoma: An evaluation of subtypes with CT and angiography

Y. Yamashita, M. Takahashi, S. Kanazawa, C. Charnsangavej, S. Wallace

Research output: Contribution to journalReview articlepeer-review

33 Citations (Scopus)


Sixty-seven patients had hilar cholangiocarcinomas which were divided into 3 types based on tumor morphology as observed on cholangiography and CT. The pathology, vascularity, and pattern of tumor spread of these types were compared. Most of the infiltrative tumors (n = 44) were scirrhous adenocarcinomas, which on CT showed poor or no contrast enhancement with frequent lymph node metastases and liver atrophy. At angiography, there was vascular encasement in 52%, in rare cases neovascularity, and tumor stain. The exophytic type (n = 19) was divided into 2 subgroups depending on the main location of the tumor. The nodular subtype (n = 16) was mainly inside the liver and somewhat hypervascular similar to peripheral cholangiocarcinoma, often with intrahepatic metastases. The periductal subtype (n = 3) was hypovascular, similar to the infiltrative cholangiocarcinoma, and had a tendency to spread along the portal vein. The intraductal type (n = 4) was observed as a filling defect on cholangiography. CT revealed an intraluminal low density mass. Histologically, they were papillary adenocarcinomas. The radiologic types of hilar cholangiocarcinoma showed different characteristics with regard to pathologic findings, vascularity, and pattern of spread.

Original languageEnglish
Pages (from-to)351-355
Number of pages5
JournalActa Radiologica
Issue number4
Publication statusPublished - Jul 1992
Externally publishedYes


  • Bile ducts
  • CT
  • angiography
  • neoplasms

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'Hilar cholangiocarcinoma: An evaluation of subtypes with CT and angiography'. Together they form a unique fingerprint.

Cite this