Hydroarylation of acetylenes, acrylates, and isocyanates with heteroaromatic compounds under rhenium catalysis

Yoichiro Kuninobu, Kou Kikuchi, Yukimi Tokunaga, Yuta Nishina, Kazuhiko Takai

Research output: Contribution to journalArticlepeer-review

79 Citations (Scopus)

Abstract

With the aid of a directing group, an imine moiety, heteroaromatic compounds add to acetylenes in the presence of a catalytic amount of [ReBr(CO)3(THF)]2 at the adjacent position of the directing group regioselectively to give hydroarylation of the acetylenes in good to excellent yields. Similarly, heteroaromatic compounds react with acrylates and isocyanates to give the corresponding hydroarylation products under rhenium catalysis.

Original languageEnglish
Pages (from-to)5974-5981
Number of pages8
JournalTetrahedron
Volume64
Issue number26
DOIs
Publication statusPublished - Jun 23 2008

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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