Abstract
A biomimetic environment fabricated with synthetic material would be an effective tool for reproducing the tissue-developmental process and even for achieving tissue engineering in vitro. A hydrogel material is one candidate for this tool, because a hydrogel normally shows harmless properties in regard to cells and tissue, and it can be tuned chemically and physically to obtain the desired form. Accordingly, fibrin gel was utilized to reproduce the 3D cellular orientations found in muscle tissue, fabricate tendon-like mineralized tissue, and regulate vascular formation. In this context, cell and tissue manipulations within the gel were led by in vitro physical and chemical stimulations. In this chapter, the approach used for manipulating cells and tissues using the designed hydrogel is discussed.
| Original language | English |
|---|---|
| Title of host publication | Interface Oral Health Science 2014 |
| Subtitle of host publication | Innovative Research on Biosis-Abiosis Intelligent Interface |
| Publisher | Springer Japan |
| Pages | 161-168 |
| Number of pages | 8 |
| ISBN (Electronic) | 9784431551928 |
| ISBN (Print) | 9784431551256 |
| DOIs | |
| Publication status | Published - Jan 1 2015 |
Keywords
- Biomimetic environment
- Cell manipulation
- Hydrogel
- In vitro tissue engineering
ASJC Scopus subject areas
- Dentistry(all)
- Medicine(all)
- Immunology and Microbiology(all)
- Biochemistry, Genetics and Molecular Biology(all)