Hydrolytic stability of three-step etch-and-rinse adhesives in occlusal class-I cavities

Jan De Munck, Atsushi Mine, Marcio Vivan Cardoso, Kirsten L. Van Landuyt, Anne Katrin Lührs, André Poitevin, Masao Hanabusa, Takuo Kuboki, Bart Van Meerbeek

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


Objectives: A dental adhesive without small and hydrophilic monomers such as 2-hydroxyethyl methacrylate (HEMA) and triethylene glycol dimethacrylate (TEGDMA) would be beneficial in order to avoid contact allergies. However, these monomers are important to increase infiltration and polymerization of the adhesive. Therefore, the purpose of this study was to evaluate the bonding effectiveness and bond durability of a more hydrophobic and biocompatible adhesive as compared to a conventional three-step etch-and-rinse adhesive. Methods: Sixteen non-carious human third molars were used to determine the micro-tensile bond strength testing (μTBS) and interfacial ultrastructure by transmission electron microscopy (TEM) of the more hydrophobic cmf adhesive system (Saremco) adhesive as compared to the control OptiBond FL (Kerr). Results: The more hydrophobic and biocompatible three-step etch-and-rinse adhesive was able to produce a reasonable short-time bonding effectiveness. In the long term, the collagen fibrils in the hybrid layer were not effectively protected and were prone to hydrolytic degradation. As a result, long-term bonding effectiveness of this novel adhesive was very low. Conclusions: Application of a more hydrophobic adhesive without altering the application procedure considerably results in a reduced durability of the created bond Clinical relevance: Omitting small and hydrophilic components from the adhesive formulation may impair the durability of your composite restoration.

Original languageEnglish
Pages (from-to)1911-1918
Number of pages8
JournalClinical Oral Investigations
Issue number8
Publication statusPublished - Nov 2013


  • Allergy
  • Bond strength
  • Class-I cavity dentin
  • Durability
  • TEM
  • Three-step etch-and-rinse

ASJC Scopus subject areas

  • Dentistry(all)


Dive into the research topics of 'Hydrolytic stability of three-step etch-and-rinse adhesives in occlusal class-I cavities'. Together they form a unique fingerprint.

Cite this