Immunohistochemical localization of calcineurin, calmodulin-stimulated phosphatase, in the rat hippocampus using a monoclonal antibody

Hideki Matsui; Akitaka Doi; Toshifumi Itano; Masahisa Shimada; Jerry H. Wang; Osamu Hatase

doi:10.1016/0006-8993(87)91067-5

Immunohistochemical localization of calcineurin, calmodulin-stimulated phosphatase, in the rat hippocampus using a monoclonal antibody

Hideki Matsui, Akitaka Doi, Toshifumi Itano, Masahisa Shimada, Jerry H. Wang, Osamu Hatase

Graduate School of Medicine Dentistry and Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

Immunohistochemical localization of calcineurin, a calmodulin-stimulated phosphatase, was examined in the rat hippocampus by using a monoclonal antibody VD₃ which is specific for the A subunit (61 kDa)_ of calcineurin. The stratum lucidum, where the mossy fiber terminal forms giant synaptic boutons, showed strong immunoreactivity.

Original language	English
Pages (from-to)	193-196
Number of pages	4
Journal	Brain Research
Volume	402
Issue number	1
DOIs	https://doi.org/10.1016/0006-8993(87)91067-5
Publication status	Published - Jan 27 1987

Keywords

Calcineurin
Calmodulin
Hippocampus
Immunohistochemistry
Peroxidase antiperoxidase method
Phosphatase
Zinc

ASJC Scopus subject areas

Neuroscience(all)
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/0006-8993(87)91067-5

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title = "Immunohistochemical localization of calcineurin, calmodulin-stimulated phosphatase, in the rat hippocampus using a monoclonal antibody",

abstract = "Immunohistochemical localization of calcineurin, a calmodulin-stimulated phosphatase, was examined in the rat hippocampus by using a monoclonal antibody VD3 which is specific for the A subunit (61 kDa)_ of calcineurin. The stratum lucidum, where the mossy fiber terminal forms giant synaptic boutons, showed strong immunoreactivity.",

keywords = "Calcineurin, Calmodulin, Hippocampus, Immunohistochemistry, Peroxidase antiperoxidase method, Phosphatase, Zinc",

author = "Hideki Matsui and Akitaka Doi and Toshifumi Itano and Masahisa Shimada and Wang, {Jerry H.} and Osamu Hatase",

note = "Funding Information: We gratefully thank Mr. Akira Miyatake for technical assistance, and Miss Toshiko Ohue and Miss Hi-sako Ohnishi for secretarial service. This work was supported by Grant-in-Aid for Scientific Research from the Ministry of Education, Science and Culture of Japan.",

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doi = "10.1016/0006-8993(87)91067-5",

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T1 - Immunohistochemical localization of calcineurin, calmodulin-stimulated phosphatase, in the rat hippocampus using a monoclonal antibody

AU - Matsui, Hideki

AU - Doi, Akitaka

AU - Itano, Toshifumi

AU - Shimada, Masahisa

AU - Wang, Jerry H.

AU - Hatase, Osamu

N1 - Funding Information: We gratefully thank Mr. Akira Miyatake for technical assistance, and Miss Toshiko Ohue and Miss Hi-sako Ohnishi for secretarial service. This work was supported by Grant-in-Aid for Scientific Research from the Ministry of Education, Science and Culture of Japan.

PY - 1987/1/27

Y1 - 1987/1/27

N2 - Immunohistochemical localization of calcineurin, a calmodulin-stimulated phosphatase, was examined in the rat hippocampus by using a monoclonal antibody VD3 which is specific for the A subunit (61 kDa)_ of calcineurin. The stratum lucidum, where the mossy fiber terminal forms giant synaptic boutons, showed strong immunoreactivity.

AB - Immunohistochemical localization of calcineurin, a calmodulin-stimulated phosphatase, was examined in the rat hippocampus by using a monoclonal antibody VD3 which is specific for the A subunit (61 kDa)_ of calcineurin. The stratum lucidum, where the mossy fiber terminal forms giant synaptic boutons, showed strong immunoreactivity.

KW - Calcineurin

KW - Calmodulin

KW - Hippocampus

KW - Immunohistochemistry

KW - Peroxidase antiperoxidase method

KW - Phosphatase

KW - Zinc

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AN - SCOPUS:0023154304

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JO - Brain Research

JF - Brain Research

IS - 1

ER -

Immunohistochemical localization of calcineurin, calmodulin-stimulated phosphatase, in the rat hippocampus using a monoclonal antibody

Abstract

Keywords

ASJC Scopus subject areas

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