Immunohistochemical studies on human brain tumors using anti-Leu 7 monoclonal antibody in paraffin-embedded specimens

M. Motoi; T. Yoshino; K. Hayashi; S. Nose; Y. Horie; K. Ogawa

doi:10.1007/BF00698299

Immunohistochemical studies on human brain tumors using anti-Leu 7 monoclonal antibody in paraffin-embedded specimens

M. Motoi, T. Yoshino, K. Hayashi, S. Nose, Y. Horie, K. Ogawa

Research output: Contribution to journal › Article › peer-review

39 Citations (Scopus)

Abstract

Using the four-step peroxidase-antiper-oxidase (PAP) method, the presence of the antigen recognized with anti-Leu 7 monoclonal antibody was investigated in paraffin-embedded human brain tissue and tumors. The antigen was demonstrated in the myelin sheaths, oligodendrocytes, and some choroid plexus cells in normal brain and in oligodendrogliomas, some astrocytomas and choroid plexus papillomas. The technique can be used to identify hormal and neoplastic oligodendrocytes.

Original language	English
Pages (from-to)	75-77
Number of pages	3
Journal	Acta neuropathologica
Volume	66
Issue number	1
DOIs	https://doi.org/10.1007/BF00698299
Publication status	Published - Mar 1985

Keywords

Anti-Leu 7
Four-step PAP method
Oligodendroglioma

ASJC Scopus subject areas

Pathology and Forensic Medicine
Clinical Neurology
Cellular and Molecular Neuroscience

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10.1007/BF00698299

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abstract = "Using the four-step peroxidase-antiper-oxidase (PAP) method, the presence of the antigen recognized with anti-Leu 7 monoclonal antibody was investigated in paraffin-embedded human brain tissue and tumors. The antigen was demonstrated in the myelin sheaths, oligodendrocytes, and some choroid plexus cells in normal brain and in oligodendrogliomas, some astrocytomas and choroid plexus papillomas. The technique can be used to identify hormal and neoplastic oligodendrocytes.",

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AU - Motoi, M.

AU - Yoshino, T.

AU - Hayashi, K.

AU - Nose, S.

AU - Horie, Y.

AU - Ogawa, K.

PY - 1985/3

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AB - Using the four-step peroxidase-antiper-oxidase (PAP) method, the presence of the antigen recognized with anti-Leu 7 monoclonal antibody was investigated in paraffin-embedded human brain tissue and tumors. The antigen was demonstrated in the myelin sheaths, oligodendrocytes, and some choroid plexus cells in normal brain and in oligodendrogliomas, some astrocytomas and choroid plexus papillomas. The technique can be used to identify hormal and neoplastic oligodendrocytes.

KW - Anti-Leu 7

KW - Four-step PAP method

KW - Oligodendroglioma

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Immunohistochemical studies on human brain tumors using anti-Leu 7 monoclonal antibody in paraffin-embedded specimens

Abstract

Keywords

ASJC Scopus subject areas

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