Impact of hydrophilicity and length of spacer chains on the bonding of functional monomers

Victor P. Feitosa, Salvatore Sauro, Fabricio A. Ogliari, Aline Oliveira Ogliari, Kumiko Yoshihara, Cesar H. Zanchi, Lourenҫo Correr-Sobrinho, Mário A. Sinhoreti, Américo B. Correr, Timothy F. Watson, Bart Van Meerbeek

Research output: Contribution to journalArticlepeer-review

65 Citations (Scopus)


Objectives. 10-Methacryloyloxy-decyl-dihydrogen-phosphate (10-MDP) is currently considered as one of the most effective functional monomers for dental bonding, this in part thanks to its long and relatively hydrophobic spacer chain, adequately separating the polymerizable from the phosphate functionalities. This study compared functional monomers with different spacer chains' length and hydrophilicity to 10-MDP on their dentin and enamel bonding performance. Methods. Atomic absorption spectroscopy (AAS) was used to characterize the chemical interaction. Micro-tensile bond strength (μTBS) and fractographic analyses were performed after 24 h and one year. Confocal micro-permeability and SEM nanoleakage assessments were also undertaken. The tested functional monomers were 2-MEP (2-carbon spacer), 10-MDP (10-carbon), 12-MDDP (12-carbon), MTEP (high hydrophilic polyether spacer chain) and CAP-P (intermediate hydrophilic ester spacer). Results. AAS revealed clear differences (p < 0.05) in monomer-calcium salt formation in this order: 12-MDDP = 10-MDP > CAP-P > MTEP > 2-MEP. The highest initial dentin μTBS was obtained using 10-MDP or 12-MDDP. After 1-year aging, a significant drop (p < 0.05) in μTBS was observed for the adhesives with MTEP (enamel and dentin), 2-MEP (enamel) and CAP-P (enamel). MTEP presented the highest micro-permeability, while 2-MEP, CAP-P and MTEP showed increased nanoleakage after aging.

Original languageEnglish
Pages (from-to)e317-e323
JournalDental Materials
Issue number12
Publication statusPublished - Dec 1 2014
Externally publishedYes


  • Adhesion
  • Durability
  • Functional monomer
  • Hydrophilicity
  • Micro-permeability
  • Self-etch adhesive

ASJC Scopus subject areas

  • General Materials Science
  • General Dentistry
  • Mechanics of Materials


Dive into the research topics of 'Impact of hydrophilicity and length of spacer chains on the bonding of functional monomers'. Together they form a unique fingerprint.

Cite this