Improvement of cell adhesiveness of poly(ethylene terephthalate) by surface modification with hydroxyapatite nanocrystals through covalent bonding

Miwa Masuda; Shoji Yasuda; Masahiro Okada; Ryoichi Tanaka; Kunio Miyatake; Tsutomu Furuzono

Improvement of cell adhesiveness of poly(ethylene terephthalate) by surface modification with hydroxyapatite nanocrystals through covalent bonding

Miwa Masuda, Shoji Yasuda, Masahiro Okada, Ryoichi Tanaka, Kunio Miyatake, Tsutomu Furuzono

Research output: Contribution to conference › Paper › peer-review

Abstract

In this study, a novel composite for a soft-tissue-compatible material was developed. A surface of poly(ethylene terephthalate) (PET) fabric was modified with nano-sized hydroxyapatite (HAp) crystals through covalent bonding. In order to make covalent bonding between the HAp crystal and the PET surface, poly(γ-methacryloxypropyl triethoxysilane) poly(MPTS) was grafted on the PET surface treated by H₂O₂. The surface modification of PET with poly(MPTS) was confirmed by the weight gaining and X-ray photoelectron spectroscopy. The chemical reaction between OH groups on the HAp crystals and ethoxysilyl groups on the PET was conducted at 80°C for 2h in reduced pressure. It was confirmed that HAp/PET composite was not toxic by microscopic observation. The cell adhesion test of HAp/PET composite will be reported on the presentation.

Original language	English
Number of pages	1
Publication status	Published - Dec 1 2005
Externally published	Yes
Event	54th SPSJ Annual Meeting 2005 - Yokohama, Japan Duration: May 25 2005 → May 27 2005

Other

Other	54th SPSJ Annual Meeting 2005
Country/Territory	Japan
City	Yokohama
Period	5/25/05 → 5/27/05

Keywords

Composite
Endothelial cells
HO
Poly(ethylene terephthalate)
Sintered hydroxyapatite

ASJC Scopus subject areas

Engineering(all)

Cite this

@conference{43317ef4fcb2409d939d93753dd68b41,

title = "Improvement of cell adhesiveness of poly(ethylene terephthalate) by surface modification with hydroxyapatite nanocrystals through covalent bonding",

abstract = "In this study, a novel composite for a soft-tissue-compatible material was developed. A surface of poly(ethylene terephthalate) (PET) fabric was modified with nano-sized hydroxyapatite (HAp) crystals through covalent bonding. In order to make covalent bonding between the HAp crystal and the PET surface, poly(γ-methacryloxypropyl triethoxysilane) poly(MPTS) was grafted on the PET surface treated by H2O2. The surface modification of PET with poly(MPTS) was confirmed by the weight gaining and X-ray photoelectron spectroscopy. The chemical reaction between OH groups on the HAp crystals and ethoxysilyl groups on the PET was conducted at 80°C for 2h in reduced pressure. It was confirmed that HAp/PET composite was not toxic by microscopic observation. The cell adhesion test of HAp/PET composite will be reported on the presentation.",

keywords = "Composite, Endothelial cells, HO, Poly(ethylene terephthalate), Sintered hydroxyapatite",

author = "Miwa Masuda and Shoji Yasuda and Masahiro Okada and Ryoichi Tanaka and Kunio Miyatake and Tsutomu Furuzono",

year = "2005",

month = dec,

day = "1",

language = "English",

note = "54th SPSJ Annual Meeting 2005 ; Conference date: 25-05-2005 Through 27-05-2005",

}

TY - CONF

T1 - Improvement of cell adhesiveness of poly(ethylene terephthalate) by surface modification with hydroxyapatite nanocrystals through covalent bonding

AU - Masuda, Miwa

AU - Yasuda, Shoji

AU - Okada, Masahiro

AU - Tanaka, Ryoichi

AU - Miyatake, Kunio

AU - Furuzono, Tsutomu

PY - 2005/12/1

Y1 - 2005/12/1

N2 - In this study, a novel composite for a soft-tissue-compatible material was developed. A surface of poly(ethylene terephthalate) (PET) fabric was modified with nano-sized hydroxyapatite (HAp) crystals through covalent bonding. In order to make covalent bonding between the HAp crystal and the PET surface, poly(γ-methacryloxypropyl triethoxysilane) poly(MPTS) was grafted on the PET surface treated by H2O2. The surface modification of PET with poly(MPTS) was confirmed by the weight gaining and X-ray photoelectron spectroscopy. The chemical reaction between OH groups on the HAp crystals and ethoxysilyl groups on the PET was conducted at 80°C for 2h in reduced pressure. It was confirmed that HAp/PET composite was not toxic by microscopic observation. The cell adhesion test of HAp/PET composite will be reported on the presentation.

AB - In this study, a novel composite for a soft-tissue-compatible material was developed. A surface of poly(ethylene terephthalate) (PET) fabric was modified with nano-sized hydroxyapatite (HAp) crystals through covalent bonding. In order to make covalent bonding between the HAp crystal and the PET surface, poly(γ-methacryloxypropyl triethoxysilane) poly(MPTS) was grafted on the PET surface treated by H2O2. The surface modification of PET with poly(MPTS) was confirmed by the weight gaining and X-ray photoelectron spectroscopy. The chemical reaction between OH groups on the HAp crystals and ethoxysilyl groups on the PET was conducted at 80°C for 2h in reduced pressure. It was confirmed that HAp/PET composite was not toxic by microscopic observation. The cell adhesion test of HAp/PET composite will be reported on the presentation.

KW - Composite

KW - Endothelial cells

KW - HO

KW - Poly(ethylene terephthalate)

KW - Sintered hydroxyapatite

UR - http://www.scopus.com/inward/record.url?scp=33645641635&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33645641635&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:33645641635

T2 - 54th SPSJ Annual Meeting 2005

Y2 - 25 May 2005 through 27 May 2005

ER -

Improvement of cell adhesiveness of poly(ethylene terephthalate) by surface modification with hydroxyapatite nanocrystals through covalent bonding

Abstract

Other

Keywords

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this