In vitro apatite deposition and biodegradation of porous gelatin-silicate hybrids derived from sol-gel process

L. Ren; K. Tsuru; S. Hayakawa; A. Osaka

doi:10.1557/proc-628-cc10.6

In vitro apatite deposition and biodegradation of porous gelatin-silicate hybrids derived from sol-gel process

L. Ren, K. Tsuru, S. Hayakawa, A. Osaka

Research output: Contribution to journal › Conference article › peer-review

1 Citation (Scopus)

Abstract

Ca(II) containing porous hybrids of gelatin and 3-(glycidoxypropyl) trimethoxysilane (GPSM) were prepared with sol-gel processing and freeze-drying techniques. The freezing temperature could control porosity and pore size of the hybrids. The biodegradation rate of the hybrids in a Tris buffer solution decreased with an increase in GPSM content. The bone-like apatite layer could form on the Ca(II) containing porous gelatin-silicate hybrids when they were soaked in a stimulated body fluid (SBF), hence they were applicable to be the bioactive scaffolds for bone tissue engineering.

Original language	English
Pages (from-to)	CC10.6.1-CC10.6.6
Journal	Materials Research Society Symposium - Proceedings
Volume	628
DOIs	https://doi.org/10.1557/proc-628-cc10.6
Publication status	Published - 2000
Event	Organic/Inorganic Hybrid Materials-2000 - San Francisco, CA, United States Duration: Apr 24 2000 → Apr 28 2000

ASJC Scopus subject areas

General Materials Science
Condensed Matter Physics
Mechanics of Materials
Mechanical Engineering

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title = "In vitro apatite deposition and biodegradation of porous gelatin-silicate hybrids derived from sol-gel process",

abstract = "Ca(II) containing porous hybrids of gelatin and 3-(glycidoxypropyl) trimethoxysilane (GPSM) were prepared with sol-gel processing and freeze-drying techniques. The freezing temperature could control porosity and pore size of the hybrids. The biodegradation rate of the hybrids in a Tris buffer solution decreased with an increase in GPSM content. The bone-like apatite layer could form on the Ca(II) containing porous gelatin-silicate hybrids when they were soaked in a stimulated body fluid (SBF), hence they were applicable to be the bioactive scaffolds for bone tissue engineering.",

author = "L. Ren and K. Tsuru and S. Hayakawa and A. Osaka",

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T1 - In vitro apatite deposition and biodegradation of porous gelatin-silicate hybrids derived from sol-gel process

AU - Ren, L.

AU - Tsuru, K.

AU - Hayakawa, S.

AU - Osaka, A.

PY - 2000

Y1 - 2000

N2 - Ca(II) containing porous hybrids of gelatin and 3-(glycidoxypropyl) trimethoxysilane (GPSM) were prepared with sol-gel processing and freeze-drying techniques. The freezing temperature could control porosity and pore size of the hybrids. The biodegradation rate of the hybrids in a Tris buffer solution decreased with an increase in GPSM content. The bone-like apatite layer could form on the Ca(II) containing porous gelatin-silicate hybrids when they were soaked in a stimulated body fluid (SBF), hence they were applicable to be the bioactive scaffolds for bone tissue engineering.

AB - Ca(II) containing porous hybrids of gelatin and 3-(glycidoxypropyl) trimethoxysilane (GPSM) were prepared with sol-gel processing and freeze-drying techniques. The freezing temperature could control porosity and pore size of the hybrids. The biodegradation rate of the hybrids in a Tris buffer solution decreased with an increase in GPSM content. The bone-like apatite layer could form on the Ca(II) containing porous gelatin-silicate hybrids when they were soaked in a stimulated body fluid (SBF), hence they were applicable to be the bioactive scaffolds for bone tissue engineering.

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SP - CC10.6.1-CC10.6.6

JO - Materials Research Society Symposium - Proceedings

JF - Materials Research Society Symposium - Proceedings

T2 - Organic/Inorganic Hybrid Materials-2000

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ER -

In vitro apatite deposition and biodegradation of porous gelatin-silicate hybrids derived from sol-gel process

Abstract

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