In vitro biodegradability of chitosan-organosiloxane hybrid membrane

K. Tsuru; Y. Shirosaki; S. Hayakawa; A. Osaka; M. A. Lopes; J. D. Santos; M. H. Fernandas

doi:10.4028/0-87849-961-x.823

In vitro biodegradability of chitosan-organosiloxane hybrid membrane

K. Tsuru, Y. Shirosaki, S. Hayakawa, A. Osaka, M. A. Lopes, J. D. Santos, M. H. Fernandas

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Chitosan-silicate hybrid membranes were prepared using γ- glycidoxypropyltrimethoxysilane (GPSM) through a sol-gel process. The amino groups of chitosan chains were reacted with the epoxy groups of GPSM and GPSM have a function as the agent to cross-link the chitosan chains. The cross-linking degree of the hybrid membranes was determined by ninhydrin assay. Fourier-transform infrared (FT-IR) spectroscopy and ²⁹Si cross-polarization (CP) magic-angle spinning (MAS)-NMR spectroscopy were used to assess the structure of the hybrid membranes. The biodegradability of the hybrid membranes in phosphate-buffered saline solution or lysozyme solution was investigated as a function of the GPSM concentration.

Original language	English
Pages (from-to)	823-826
Number of pages	4
Journal	Key Engineering Materials
Volume	284-286
DOIs	https://doi.org/10.4028/0-87849-961-x.823
Publication status	Published - Jan 1 2005

Keywords

Biodegradability
Chitosan
Chitosan-lnorganlc hybrid
R- glycidoxypropyltrimethoxysilane GPSM

ASJC Scopus subject areas

Materials Science(all)
Mechanics of Materials
Mechanical Engineering

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Cite this

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abstract = "Chitosan-silicate hybrid membranes were prepared using γ- glycidoxypropyltrimethoxysilane (GPSM) through a sol-gel process. The amino groups of chitosan chains were reacted with the epoxy groups of GPSM and GPSM have a function as the agent to cross-link the chitosan chains. The cross-linking degree of the hybrid membranes was determined by ninhydrin assay. Fourier-transform infrared (FT-IR) spectroscopy and 29Si cross-polarization (CP) magic-angle spinning (MAS)-NMR spectroscopy were used to assess the structure of the hybrid membranes. The biodegradability of the hybrid membranes in phosphate-buffered saline solution or lysozyme solution was investigated as a function of the GPSM concentration.",

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AU - Tsuru, K.

AU - Shirosaki, Y.

AU - Hayakawa, S.

AU - Osaka, A.

AU - Lopes, M. A.

AU - Santos, J. D.

AU - Fernandas, M. H.

PY - 2005/1/1

Y1 - 2005/1/1

N2 - Chitosan-silicate hybrid membranes were prepared using γ- glycidoxypropyltrimethoxysilane (GPSM) through a sol-gel process. The amino groups of chitosan chains were reacted with the epoxy groups of GPSM and GPSM have a function as the agent to cross-link the chitosan chains. The cross-linking degree of the hybrid membranes was determined by ninhydrin assay. Fourier-transform infrared (FT-IR) spectroscopy and 29Si cross-polarization (CP) magic-angle spinning (MAS)-NMR spectroscopy were used to assess the structure of the hybrid membranes. The biodegradability of the hybrid membranes in phosphate-buffered saline solution or lysozyme solution was investigated as a function of the GPSM concentration.

AB - Chitosan-silicate hybrid membranes were prepared using γ- glycidoxypropyltrimethoxysilane (GPSM) through a sol-gel process. The amino groups of chitosan chains were reacted with the epoxy groups of GPSM and GPSM have a function as the agent to cross-link the chitosan chains. The cross-linking degree of the hybrid membranes was determined by ninhydrin assay. Fourier-transform infrared (FT-IR) spectroscopy and 29Si cross-polarization (CP) magic-angle spinning (MAS)-NMR spectroscopy were used to assess the structure of the hybrid membranes. The biodegradability of the hybrid membranes in phosphate-buffered saline solution or lysozyme solution was investigated as a function of the GPSM concentration.

KW - Biodegradability

KW - Chitosan

KW - Chitosan-lnorganlc hybrid

KW - R- glycidoxypropyltrimethoxysilane GPSM

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In vitro biodegradability of chitosan-organosiloxane hybrid membrane

Abstract

Keywords

ASJC Scopus subject areas

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