Abstract
Chitosan-silicate hybrids were synthesized using γ-glycidoxypropyltrimethoxysilane (GPSM) as the agent to cross-link the chitosan chains. Fourier-transform infrared (PT-IR) spectroscopy was used to analyze the structures of the hybrids. The swelling ability and the cytocompatibility of the hybrids were investigated as a function of the GPSM concentration. The swelling of the hybrids was suppressed by addition of GPSM. MG63 human osteoblastic cells were cultured on the hybrids. The adhesion and proliferation of the MG63 cells cultured on the chitosan-GPSM hybrid surface were improved comparing to that on chitosan membrane, regardless the GPSM concentration.
| Original language | English |
|---|---|
| Pages (from-to) | 857-860 |
| Number of pages | 4 |
| Journal | Key Engineering Materials |
| Volume | 254-256 |
| Publication status | Published - 2004 |
| Event | The Annual Meeting of the International Society for Ceramics in Medicine - Porto, Portugal Duration: Nov 6 2003 → Nov 9 2003 |
Keywords
- Chitosan
- Chitosan-inorganic hybrid
- Cytocompatibility
- Osteoblastic cell (MG63)
- γ-glycidoxypropyltrimethoxysilane (GPSM)
ASJC Scopus subject areas
- General Materials Science
- Mechanics of Materials
- Mechanical Engineering