In vitro susceptibilites to levofloxacin and various antibacterial agents of 18,639 clinical isolates obtained from 77 centers in 2004

Keizo Yamaguchi; Akira Ohno; Yoshikazu Ishii; Kazuhiro Tateda; Morihiro Iwata; Makoto Kanda; Yoshiko Tsujio; Hiroya Kimoto; Masaharu Nishimura; Koji Akizawa; Keiko Matsuda; Tasuku Hayashi; Makoto Tominaga; Takuo Nakagawa; Shunkoh Toyoshima; Akihiro Sugita; Tatsumi Ito; Akira Suwabe; Kumiko Yamahata; Mitsuomi Kaimori; Toshihiko Nakamura; Chizuko Kawamura; Yosei Katayama; Minoru Yasujima; Takeshi Kasai; Masahiko Kimura; Makoto Miki; Susumu Nakanowatari; Mitsuo Kaku; Keiji Kanemitsu; Hiroyuki Kunishima; Masanori Sakurai; Joji Shiotani; Jun Okada; Akiko Yoneyama; Kazunari Kumasaka; Kazuhiko Koike; Hidenori Kominami; Toshiyuki Yamada; Toyoko Oguri; Kiyoaki Watanabe; Yoshio Kobayashi; Teruko Ohtake; Kyoichi Totsuka; Hideyuki Okamoto; Kenichiro Yamazaki; Motoi Okada; Hiromi Ikari; Naomi Kurosawa; Mori Mikio; Ichino Kano; Eiko Nagano; Harushige Kanno; Masanori Aihara; Shighefumi Maesaki; Giichi Hashikita; Eiji Miyajima; Midori Sumitomo; Nobuo Yamane; Tamio Ieiri; Kouichi Itoh; Takashi Uchida; Masami Murakami; Sachie Yomoda; Ayako Takahashi; Kazuhisa Inuzuka; Hideo Gonda; Takanori Yamashita; Ikuo Yamaguchi; Yoshinori Fujimoto; Shiomi Ishigo; Yuko Asano; Fumio Kageyama; Etsuko Shaku; Hitoshi Gemma; Keiichi Uemura; Toshinobu Horii; Hitoshi Yoshimura; Minoru Hiraoka; Hideo Wada; Hisashi Baba; Satoshi Ichiyama; Shinichi Fujita; Hidetoshi Okabe; Kenichi Tatewaki; Kunihiko Moro; Haruyoshi Yoshida; Masanobu Yamashita; Takeshi Fushiwaki; Akira Shimizu; Takayuki Takubo; Tadashi Kusakabe; Hakuo Takahashi; Hitoshi Heijyou; Koji Asai; Kunimitsu Kawahara; Reiko Sano; Syuji Matsuo; Masaru Komatsu; Yosuke Yuzuki; Norio Ikeda; Masayuki Soma; Tsuyoshi Yamamoto; Syohiro Kinosita; Seiji Kawano; Takeshi Kageoka; Toshiharu Kongo; Mikio Oka; Yoshihito Niki; Nobuchika Kusano; Eiichiro Mihara; Motoko Nose; Masao Kuwabara; Yoshihiro Fujiue; Yuji Hinoda; Nobuaki Tanaka; Toshiro Okazaki; Junichi Masuda; Tomohiko Taminato; Kiyoshi Negayama; Tetsuro Sugiura; Mitsuharu Murase; Nobuhisa Yamane; Isao Nakasone; Hisamichi Aizawa; Junichi Honda; Akihiko Okayama; Yosuke Aoki; Hiroaki Miyanohara; Kazufumi Hiramatsu; Yoichi Hirakata; Shigeru Kohno; Naotaka Hamazaki; Junko Ono; Kaoru Okada

In vitro susceptibilites to levofloxacin and various antibacterial agents of 18,639 clinical isolates obtained from 77 centers in 2004

Keizo Yamaguchi, Akira Ohno, Yoshikazu Ishii, Kazuhiro Tateda, Morihiro Iwata, Makoto Kanda, Yoshiko Tsujio, Hiroya Kimoto, Masaharu Nishimura, Koji Akizawa, Keiko Matsuda, Tasuku Hayashi, Makoto Tominaga, Takuo Nakagawa, Shunkoh Toyoshima, Akihiro Sugita, Tatsumi Ito, Akira Suwabe, Kumiko Yamahata, Mitsuomi KaimoriToshihiko Nakamura, Chizuko Kawamura, Yosei Katayama, Minoru Yasujima, Takeshi Kasai, Masahiko Kimura, Makoto Miki, Susumu Nakanowatari, Mitsuo Kaku, Keiji Kanemitsu, Hiroyuki Kunishima, Masanori Sakurai, Joji Shiotani, Jun Okada, Akiko Yoneyama, Kazunari Kumasaka, Kazuhiko Koike, Hidenori Kominami, Toshiyuki Yamada, Toyoko Oguri, Kiyoaki Watanabe, Yoshio Kobayashi, Teruko Ohtake, Kyoichi Totsuka, Hideyuki Okamoto, Kenichiro Yamazaki, Motoi Okada, Hiromi Ikari, Naomi Kurosawa, Mori Mikio, Ichino Kano, Eiko Nagano, Harushige Kanno, Masanori Aihara, Shighefumi Maesaki, Giichi Hashikita, Eiji Miyajima, Midori Sumitomo, Nobuo Yamane, Tamio Ieiri, Kouichi Itoh, Takashi Uchida, Masami Murakami, Sachie Yomoda, Ayako Takahashi, Kazuhisa Inuzuka, Hideo Gonda, Takanori Yamashita, Ikuo Yamaguchi, Yoshinori Fujimoto, Shiomi Ishigo, Yuko Asano, Fumio Kageyama, Etsuko Shaku, Hitoshi Gemma, Keiichi Uemura, Toshinobu Horii, Hitoshi Yoshimura, Minoru Hiraoka, Hideo Wada, Hisashi Baba, Satoshi Ichiyama, Shinichi Fujita, Hidetoshi Okabe, Kenichi Tatewaki, Kunihiko Moro, Haruyoshi Yoshida, Masanobu Yamashita, Takeshi Fushiwaki, Akira Shimizu, Takayuki Takubo, Tadashi Kusakabe, Hakuo Takahashi, Hitoshi Heijyou, Koji Asai, Kunimitsu Kawahara, Reiko Sano, Syuji Matsuo, Masaru Komatsu, Yosuke Yuzuki, Norio Ikeda, Masayuki Soma, Tsuyoshi Yamamoto, Syohiro Kinosita, Seiji Kawano, Takeshi Kageoka, Toshiharu Kongo, Mikio Oka, Yoshihito Niki, Nobuchika Kusano, Eiichiro Mihara, Motoko Nose, Masao Kuwabara, Yoshihiro Fujiue, Yuji Hinoda, Nobuaki Tanaka, Toshiro Okazaki, Junichi Masuda, Tomohiko Taminato, Kiyoshi Negayama, Tetsuro Sugiura, Mitsuharu Murase, Nobuhisa Yamane, Isao Nakasone, Hisamichi Aizawa, Junichi Honda, Akihiko Okayama, Yosuke Aoki, Hiroaki Miyanohara, Kazufumi Hiramatsu, Yoichi Hirakata, Shigeru Kohno, Naotaka Hamazaki, Junko Ono, Kaoru Okada

University Hospital

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

Abstract

A total of 18,639 clinical isolates in 19 species collected from 77 centers during 2004 in Japan were tested for their susceptibility to fluoroquinolones (FQs) and other selected antibiotics. The common respiratory pathogens, Streptococcus pyogenes, Streptococcus pneumoniae, Moraxella catarrhalis and Haemophilus influenzae showed a high susceptible rate against FQs. The isolation rate of beta lactamase non-producing ampicillin-resistant H. influenzae was approximately three times as large as those of western countries. Most strains of Enterobacteriaceae were also susceptible to FQs. The resistance rate of Escherichia coli against FQs has however been rapidly increasing so far as we surveyed since 1994. The FQs-resistant rate in methicillin-resistant Staphylococcus aureus (MRSA) showed approximately 90% except for 36% of sitafloxacin while FQs-resistant rate in methicillin-susceptible S. aureus (MSSA) was around 5%. The FQs-resistant rate of methicillin-resistant coagulase negative Staphylococci (MRCNS) was also higher than that of methicillin- susceptible coagulase negative Staphylococci (MSCNS), however, it was lower than that of MRSA. In Pseudomonas aeruginosa clinical isolates, 32-34% from UTI and 15-19% of from RTI was resistant to FQs. Acinetobacter spp. showed a high susceptibility to FQs. Although FQs-resistant Neisseria gonorrhoeae have not been increased in western countries, it is remarkably high in Japan. In this survey, isolates of approximately 85% was resistant to FQs.

Original language	English
Pages (from-to)	428-451
Number of pages	24
Journal	Japanese Journal of Antibiotics
Volume	59
Issue number	6
Publication status	Published - Dec 2006

ASJC Scopus subject areas

Microbiology (medical)
Pharmacology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

Yamaguchi, K., Ohno, A., Ishii, Y., Tateda, K., Iwata, M., Kanda, M., Tsujio, Y., Kimoto, H., Nishimura, M., Akizawa, K., Matsuda, K., Hayashi, T., Tominaga, M., Nakagawa, T., Toyoshima, S., Sugita, A., Ito, T., Suwabe, A., Yamahata, K., ... Okada, K. (2006). In vitro susceptibilites to levofloxacin and various antibacterial agents of 18,639 clinical isolates obtained from 77 centers in 2004. Japanese Journal of Antibiotics, 59(6), 428-451.

Yamaguchi, K, Ohno, A, Ishii, Y, Tateda, K, Iwata, M, Kanda, M, Tsujio, Y, Kimoto, H, Nishimura, M, Akizawa, K, Matsuda, K, Hayashi, T, Tominaga, M, Nakagawa, T, Toyoshima, S, Sugita, A, Ito, T, Suwabe, A, Yamahata, K, Kaimori, M, Nakamura, T, Kawamura, C, Katayama, Y, Yasujima, M, Kasai, T, Kimura, M, Miki, M, Nakanowatari, S, Kaku, M, Kanemitsu, K, Kunishima, H, Sakurai, M, Shiotani, J, Okada, J, Yoneyama, A, Kumasaka, K, Koike, K, Kominami, H, Yamada, T, Oguri, T, Watanabe, K, Kobayashi, Y, Ohtake, T, Totsuka, K, Okamoto, H, Yamazaki, K, Okada, M, Ikari, H, Kurosawa, N, Mikio, M, Kano, I, Nagano, E, Kanno, H, Aihara, M, Maesaki, S, Hashikita, G, Miyajima, E, Sumitomo, M, Yamane, N, Ieiri, T, Itoh, K, Uchida, T, Murakami, M, Yomoda, S, Takahashi, A, Inuzuka, K, Gonda, H, Yamashita, T, Yamaguchi, I, Fujimoto, Y, Ishigo, S, Asano, Y, Kageyama, F, Shaku, E, Gemma, H, Uemura, K, Horii, T, Yoshimura, H, Hiraoka, M, Wada, H, Baba, H, Ichiyama, S, Fujita, S, Okabe, H, Tatewaki, K, Moro, K, Yoshida, H, Yamashita, M, Fushiwaki, T, Shimizu, A, Takubo, T, Kusakabe, T, Takahashi, H, Heijyou, H, Asai, K, Kawahara, K, Sano, R, Matsuo, S, Komatsu, M, Yuzuki, Y, Ikeda, N, Soma, M, Yamamoto, T, Kinosita, S, Kawano, S, Kageoka, T, Kongo, T, Oka, M, Niki, Y, Kusano, N, Mihara, E, Nose, M, Kuwabara, M, Fujiue, Y, Hinoda, Y, Tanaka, N, Okazaki, T, Masuda, J, Taminato, T, Negayama, K, Sugiura, T, Murase, M, Yamane, N, Nakasone, I, Aizawa, H, Honda, J, Okayama, A, Aoki, Y, Miyanohara, H, Hiramatsu, K, Hirakata, Y, Kohno, S, Hamazaki, N, Ono, J & Okada, K 2006, 'In vitro susceptibilites to levofloxacin and various antibacterial agents of 18,639 clinical isolates obtained from 77 centers in 2004', Japanese Journal of Antibiotics, vol. 59, no. 6, pp. 428-451.

@article{be558f954e894a0a96daf8d872621df2,

title = "In vitro susceptibilites to levofloxacin and various antibacterial agents of 18,639 clinical isolates obtained from 77 centers in 2004",

abstract = "A total of 18,639 clinical isolates in 19 species collected from 77 centers during 2004 in Japan were tested for their susceptibility to fluoroquinolones (FQs) and other selected antibiotics. The common respiratory pathogens, Streptococcus pyogenes, Streptococcus pneumoniae, Moraxella catarrhalis and Haemophilus influenzae showed a high susceptible rate against FQs. The isolation rate of beta lactamase non-producing ampicillin-resistant H. influenzae was approximately three times as large as those of western countries. Most strains of Enterobacteriaceae were also susceptible to FQs. The resistance rate of Escherichia coli against FQs has however been rapidly increasing so far as we surveyed since 1994. The FQs-resistant rate in methicillin-resistant Staphylococcus aureus (MRSA) showed approximately 90% except for 36% of sitafloxacin while FQs-resistant rate in methicillin-susceptible S. aureus (MSSA) was around 5%. The FQs-resistant rate of methicillin-resistant coagulase negative Staphylococci (MRCNS) was also higher than that of methicillin- susceptible coagulase negative Staphylococci (MSCNS), however, it was lower than that of MRSA. In Pseudomonas aeruginosa clinical isolates, 32-34% from UTI and 15-19% of from RTI was resistant to FQs. Acinetobacter spp. showed a high susceptibility to FQs. Although FQs-resistant Neisseria gonorrhoeae have not been increased in western countries, it is remarkably high in Japan. In this survey, isolates of approximately 85% was resistant to FQs.",

author = "Keizo Yamaguchi and Akira Ohno and Yoshikazu Ishii and Kazuhiro Tateda and Morihiro Iwata and Makoto Kanda and Yoshiko Tsujio and Hiroya Kimoto and Masaharu Nishimura and Koji Akizawa and Keiko Matsuda and Tasuku Hayashi and Makoto Tominaga and Takuo Nakagawa and Shunkoh Toyoshima and Akihiro Sugita and Tatsumi Ito and Akira Suwabe and Kumiko Yamahata and Mitsuomi Kaimori and Toshihiko Nakamura and Chizuko Kawamura and Yosei Katayama and Minoru Yasujima and Takeshi Kasai and Masahiko Kimura and Makoto Miki and Susumu Nakanowatari and Mitsuo Kaku and Keiji Kanemitsu and Hiroyuki Kunishima and Masanori Sakurai and Joji Shiotani and Jun Okada and Akiko Yoneyama and Kazunari Kumasaka and Kazuhiko Koike and Hidenori Kominami and Toshiyuki Yamada and Toyoko Oguri and Kiyoaki Watanabe and Yoshio Kobayashi and Teruko Ohtake and Kyoichi Totsuka and Hideyuki Okamoto and Kenichiro Yamazaki and Motoi Okada and Hiromi Ikari and Naomi Kurosawa and Mori Mikio and Ichino Kano and Eiko Nagano and Harushige Kanno and Masanori Aihara and Shighefumi Maesaki and Giichi Hashikita and Eiji Miyajima and Midori Sumitomo and Nobuo Yamane and Tamio Ieiri and Kouichi Itoh and Takashi Uchida and Masami Murakami and Sachie Yomoda and Ayako Takahashi and Kazuhisa Inuzuka and Hideo Gonda and Takanori Yamashita and Ikuo Yamaguchi and Yoshinori Fujimoto and Shiomi Ishigo and Yuko Asano and Fumio Kageyama and Etsuko Shaku and Hitoshi Gemma and Keiichi Uemura and Toshinobu Horii and Hitoshi Yoshimura and Minoru Hiraoka and Hideo Wada and Hisashi Baba and Satoshi Ichiyama and Shinichi Fujita and Hidetoshi Okabe and Kenichi Tatewaki and Kunihiko Moro and Haruyoshi Yoshida and Masanobu Yamashita and Takeshi Fushiwaki and Akira Shimizu and Takayuki Takubo and Tadashi Kusakabe and Hakuo Takahashi and Hitoshi Heijyou and Koji Asai and Kunimitsu Kawahara and Reiko Sano and Syuji Matsuo and Masaru Komatsu and Yosuke Yuzuki and Norio Ikeda and Masayuki Soma and Tsuyoshi Yamamoto and Syohiro Kinosita and Seiji Kawano and Takeshi Kageoka and Toshiharu Kongo and Mikio Oka and Yoshihito Niki and Nobuchika Kusano and Eiichiro Mihara and Motoko Nose and Masao Kuwabara and Yoshihiro Fujiue and Yuji Hinoda and Nobuaki Tanaka and Toshiro Okazaki and Junichi Masuda and Tomohiko Taminato and Kiyoshi Negayama and Tetsuro Sugiura and Mitsuharu Murase and Nobuhisa Yamane and Isao Nakasone and Hisamichi Aizawa and Junichi Honda and Akihiko Okayama and Yosuke Aoki and Hiroaki Miyanohara and Kazufumi Hiramatsu and Yoichi Hirakata and Shigeru Kohno and Naotaka Hamazaki and Junko Ono and Kaoru Okada",

year = "2006",

month = dec,

language = "English",

volume = "59",

pages = "428--451",

journal = "The Journal of antibiotics. Ser. B",

issn = "0368-2781",

publisher = "Japan Antibiotics Research Association",

number = "6",

}

TY - JOUR

T1 - In vitro susceptibilites to levofloxacin and various antibacterial agents of 18,639 clinical isolates obtained from 77 centers in 2004

AU - Yamaguchi, Keizo

AU - Ohno, Akira

AU - Ishii, Yoshikazu

AU - Tateda, Kazuhiro

AU - Iwata, Morihiro

AU - Kanda, Makoto

AU - Tsujio, Yoshiko

AU - Kimoto, Hiroya

AU - Nishimura, Masaharu

AU - Akizawa, Koji

AU - Matsuda, Keiko

AU - Hayashi, Tasuku

AU - Tominaga, Makoto

AU - Nakagawa, Takuo

AU - Toyoshima, Shunkoh

AU - Sugita, Akihiro

AU - Ito, Tatsumi

AU - Suwabe, Akira

AU - Yamahata, Kumiko

AU - Kaimori, Mitsuomi

AU - Nakamura, Toshihiko

AU - Kawamura, Chizuko

AU - Katayama, Yosei

AU - Yasujima, Minoru

AU - Kasai, Takeshi

AU - Kimura, Masahiko

AU - Miki, Makoto

AU - Nakanowatari, Susumu

AU - Kaku, Mitsuo

AU - Kanemitsu, Keiji

AU - Kunishima, Hiroyuki

AU - Sakurai, Masanori

AU - Shiotani, Joji

AU - Okada, Jun

AU - Yoneyama, Akiko

AU - Kumasaka, Kazunari

AU - Koike, Kazuhiko

AU - Kominami, Hidenori

AU - Yamada, Toshiyuki

AU - Oguri, Toyoko

AU - Watanabe, Kiyoaki

AU - Kobayashi, Yoshio

AU - Ohtake, Teruko

AU - Totsuka, Kyoichi

AU - Okamoto, Hideyuki

AU - Yamazaki, Kenichiro

AU - Okada, Motoi

AU - Ikari, Hiromi

AU - Kurosawa, Naomi

AU - Mikio, Mori

AU - Kano, Ichino

AU - Nagano, Eiko

AU - Kanno, Harushige

AU - Aihara, Masanori

AU - Maesaki, Shighefumi

AU - Hashikita, Giichi

AU - Miyajima, Eiji

AU - Sumitomo, Midori

AU - Yamane, Nobuo

AU - Ieiri, Tamio

AU - Itoh, Kouichi

AU - Uchida, Takashi

AU - Murakami, Masami

AU - Yomoda, Sachie

AU - Takahashi, Ayako

AU - Inuzuka, Kazuhisa

AU - Gonda, Hideo

AU - Yamashita, Takanori

AU - Yamaguchi, Ikuo

AU - Fujimoto, Yoshinori

AU - Ishigo, Shiomi

AU - Asano, Yuko

AU - Kageyama, Fumio

AU - Shaku, Etsuko

AU - Gemma, Hitoshi

AU - Uemura, Keiichi

AU - Horii, Toshinobu

AU - Yoshimura, Hitoshi

AU - Hiraoka, Minoru

AU - Wada, Hideo

AU - Baba, Hisashi

AU - Ichiyama, Satoshi

AU - Fujita, Shinichi

AU - Okabe, Hidetoshi

AU - Tatewaki, Kenichi

AU - Moro, Kunihiko

AU - Yoshida, Haruyoshi

AU - Yamashita, Masanobu

AU - Fushiwaki, Takeshi

AU - Shimizu, Akira

AU - Takubo, Takayuki

AU - Kusakabe, Tadashi

AU - Takahashi, Hakuo

AU - Heijyou, Hitoshi

AU - Asai, Koji

AU - Kawahara, Kunimitsu

AU - Sano, Reiko

AU - Matsuo, Syuji

AU - Komatsu, Masaru

AU - Yuzuki, Yosuke

AU - Ikeda, Norio

AU - Soma, Masayuki

AU - Yamamoto, Tsuyoshi

AU - Kinosita, Syohiro

AU - Kawano, Seiji

AU - Kageoka, Takeshi

AU - Kongo, Toshiharu

AU - Oka, Mikio

AU - Niki, Yoshihito

AU - Kusano, Nobuchika

AU - Mihara, Eiichiro

AU - Nose, Motoko

AU - Kuwabara, Masao

AU - Fujiue, Yoshihiro

AU - Hinoda, Yuji

AU - Tanaka, Nobuaki

AU - Okazaki, Toshiro

AU - Masuda, Junichi

AU - Taminato, Tomohiko

AU - Negayama, Kiyoshi

AU - Sugiura, Tetsuro

AU - Murase, Mitsuharu

AU - Yamane, Nobuhisa

AU - Nakasone, Isao

AU - Aizawa, Hisamichi

AU - Honda, Junichi

AU - Okayama, Akihiko

AU - Aoki, Yosuke

AU - Miyanohara, Hiroaki

AU - Hiramatsu, Kazufumi

AU - Hirakata, Yoichi

AU - Kohno, Shigeru

AU - Hamazaki, Naotaka

AU - Ono, Junko

AU - Okada, Kaoru

PY - 2006/12

Y1 - 2006/12

N2 - A total of 18,639 clinical isolates in 19 species collected from 77 centers during 2004 in Japan were tested for their susceptibility to fluoroquinolones (FQs) and other selected antibiotics. The common respiratory pathogens, Streptococcus pyogenes, Streptococcus pneumoniae, Moraxella catarrhalis and Haemophilus influenzae showed a high susceptible rate against FQs. The isolation rate of beta lactamase non-producing ampicillin-resistant H. influenzae was approximately three times as large as those of western countries. Most strains of Enterobacteriaceae were also susceptible to FQs. The resistance rate of Escherichia coli against FQs has however been rapidly increasing so far as we surveyed since 1994. The FQs-resistant rate in methicillin-resistant Staphylococcus aureus (MRSA) showed approximately 90% except for 36% of sitafloxacin while FQs-resistant rate in methicillin-susceptible S. aureus (MSSA) was around 5%. The FQs-resistant rate of methicillin-resistant coagulase negative Staphylococci (MRCNS) was also higher than that of methicillin- susceptible coagulase negative Staphylococci (MSCNS), however, it was lower than that of MRSA. In Pseudomonas aeruginosa clinical isolates, 32-34% from UTI and 15-19% of from RTI was resistant to FQs. Acinetobacter spp. showed a high susceptibility to FQs. Although FQs-resistant Neisseria gonorrhoeae have not been increased in western countries, it is remarkably high in Japan. In this survey, isolates of approximately 85% was resistant to FQs.

AB - A total of 18,639 clinical isolates in 19 species collected from 77 centers during 2004 in Japan were tested for their susceptibility to fluoroquinolones (FQs) and other selected antibiotics. The common respiratory pathogens, Streptococcus pyogenes, Streptococcus pneumoniae, Moraxella catarrhalis and Haemophilus influenzae showed a high susceptible rate against FQs. The isolation rate of beta lactamase non-producing ampicillin-resistant H. influenzae was approximately three times as large as those of western countries. Most strains of Enterobacteriaceae were also susceptible to FQs. The resistance rate of Escherichia coli against FQs has however been rapidly increasing so far as we surveyed since 1994. The FQs-resistant rate in methicillin-resistant Staphylococcus aureus (MRSA) showed approximately 90% except for 36% of sitafloxacin while FQs-resistant rate in methicillin-susceptible S. aureus (MSSA) was around 5%. The FQs-resistant rate of methicillin-resistant coagulase negative Staphylococci (MRCNS) was also higher than that of methicillin- susceptible coagulase negative Staphylococci (MSCNS), however, it was lower than that of MRSA. In Pseudomonas aeruginosa clinical isolates, 32-34% from UTI and 15-19% of from RTI was resistant to FQs. Acinetobacter spp. showed a high susceptibility to FQs. Although FQs-resistant Neisseria gonorrhoeae have not been increased in western countries, it is remarkably high in Japan. In this survey, isolates of approximately 85% was resistant to FQs.

UR - http://www.scopus.com/inward/record.url?scp=33846810157&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846810157&partnerID=8YFLogxK

M3 - Article

C2 - 17334061

AN - SCOPUS:33846810157

SN - 0368-2781

VL - 59

SP - 428

EP - 451

JO - The Journal of antibiotics. Ser. B

JF - The Journal of antibiotics. Ser. B

IS - 6

ER -

In vitro susceptibilites to levofloxacin and various antibacterial agents of 18,639 clinical isolates obtained from 77 centers in 2004

Abstract

ASJC Scopus subject areas

UN SDGs

Other files and links

Fingerprint

Cite this