TY - JOUR
T1 - In vivo characteristics of a transplantable Marek's disease lymphoblastoid cell line, MDCC-MSB1-41C.
AU - Matsuda, H.
AU - Okamoto, J.
AU - Sekiya, Y.
AU - Yamada, M.
AU - Uno, F.
AU - Murata, M.
AU - Nii, S.
N1 - Copyright:
Copyright 2018 Medline is the source for the citation and abstract of this record.
PY - 1983
Y1 - 1983
N2 - A Marek's disease (MD) lymphoblastoid cell line, MDCC-MSB1-41C, was highly transplantable and lethal for chickens. Autopsies showed extensive metastasis in various organs. The transplantabilities of the parent cell line, MDCC-MSB1, and another derivative line, MDCC-MSB1-33C, were transient. MD virus (MDV) could be isolated from the kidneys but not from the peripheral blood leukocytes of chickens inoculated with the MSB1-41C cell line. In addition, anti-MDV antibodies were produced both in chickens inoculated with this cell line and in controls raised with inoculated chickens, but several attempts to isolate MDV from this cell line in vitro failed.
AB - A Marek's disease (MD) lymphoblastoid cell line, MDCC-MSB1-41C, was highly transplantable and lethal for chickens. Autopsies showed extensive metastasis in various organs. The transplantabilities of the parent cell line, MDCC-MSB1, and another derivative line, MDCC-MSB1-33C, were transient. MD virus (MDV) could be isolated from the kidneys but not from the peripheral blood leukocytes of chickens inoculated with the MSB1-41C cell line. In addition, anti-MDV antibodies were produced both in chickens inoculated with this cell line and in controls raised with inoculated chickens, but several attempts to isolate MDV from this cell line in vitro failed.
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U2 - 10.2307/1590200
DO - 10.2307/1590200
M3 - Article
C2 - 6316900
AN - SCOPUS:0020838676
SN - 0005-2086
VL - 27
SP - 992
EP - 1001
JO - Avian Diseases
JF - Avian Diseases
IS - 4
ER -