TY - JOUR
T1 - Induction by parathyroid hormone of ornithine decarboxylase in rabbit costal chondrocytes in culture
AU - Takigawa, Masaharu
AU - Watanabe, Rinzo
AU - Ishida, Hiroshi
AU - Asada, Akira
AU - Suzuki, Fujio
N1 - Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 1979/1
Y1 - 1979/1
N2 - The activity of ornithine decarboxylase (ODC) in rabbit costal chondrocytes in culture markedly increased after addition of parathyroid hormone (PTH), reaching a maximum 4 to 5 h after PTH addition. The effect of PTH was dose-dependent both in the presence and absence of fetal calf serum. Addition of cycloheximide or actinomycin D prevented the induction of ODC by PTH. Calcitonin, 1,25-dihydroxyvitamin D3 and vitamin A had no stimulatory effect on the activity of ODC, and did not inhibit the induction of ODC by PTH, when added with PTH.
AB - The activity of ornithine decarboxylase (ODC) in rabbit costal chondrocytes in culture markedly increased after addition of parathyroid hormone (PTH), reaching a maximum 4 to 5 h after PTH addition. The effect of PTH was dose-dependent both in the presence and absence of fetal calf serum. Addition of cycloheximide or actinomycin D prevented the induction of ODC by PTH. Calcitonin, 1,25-dihydroxyvitamin D3 and vitamin A had no stimulatory effect on the activity of ODC, and did not inhibit the induction of ODC by PTH, when added with PTH.
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U2 - 10.1093/oxfordjournals.jbchem.a132326
DO - 10.1093/oxfordjournals.jbchem.a132326
M3 - Article
C2 - 762050
AN - SCOPUS:0018771107
SN - 0021-924X
VL - 85
SP - 311
EP - 314
JO - Journal of Biochemistry
JF - Journal of Biochemistry
IS - 1
ER -