Inhibition of artificial secondary caries by fluoride-releasing adhesives on root dentin

T. Itota, S. Nakabo, Y. Iwai, N. Konishi, M. Nagamine, Y. Torii

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49 Citations (Scopus)


Fluoride-releasing materials can be expected to inhibit the secondary caries. The aim of this study was to evaluate the effect of fluoride-releasing adhesives on inhibition of secondary caries in outer and wall lesions. Two commercial fluoride-releasing adhesives, Reactmer bond (RB) and One-up bond F (OB), and a commercial adhesive without fluoride release, Mac-bond II (MB), were used prior to placement of restorative materials without fluoride release, Lite-fil II A (LF) and Estelite (EL), and a fluoride-releasing restorative material, Reactmer paste (RP). Class V cavities prepared on extracted human premolars were restored with various combinations of the materials: MB/EL, OB/EL, RB/LF and RB/RP. The restored teeth were incubated in bacterial medium containing sucrose with Streptoccus mutans for 14 days. Microradiographs of specimens showed no wall lesions in all groups and an acid-resistant layer adjacent to the restoration in the caries-like lesion. OB/EL, RB/LF and RB/RP groups showed thicker layers than the MB/EL group. The RB/RP group formed the shallowest outer lesion among all groups. These results indicate that fluoride-releasing adhesives are effective in the prevention of wall lesions but exhibit little outer lesion inhibition. Therefore, combined restoration using a fluoride-releasing adhesive and fluoride-releasing restorative material should be selected to inhibit secondary caries.

Original languageEnglish
Pages (from-to)523-527
Number of pages5
JournalJournal of oral rehabilitation
Issue number6
Publication statusPublished - Jun 2002


  • Adhesive
  • Fluoride
  • Secondary caries

ASJC Scopus subject areas

  • Dentistry(all)


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