Inhibitory effects of beer on mutation in the ames test and DNA adduct formation in mouse organs induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP)

Chemical Compounds

• PhIP 96%
• Mutation 53%
• Adduct 45%
• Pyridine 44%
• Amine 40%
• Protective 31%
• Genotoxicity 31%
• Antigenotoxic 21%
• Food Additive 15%
• Genotoxic 15%
• Demethylation 15%
• Enzyme Activity 10%
• Metabolic 10%
• Pharmacological Metabolism 9%
• Amount 5%

Medicine & Life Sciences

• 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine 100%
• DNA Adducts 79%
• Mutation 35%
• Amines 33%
• 2-amino-1-methyl-6-phenolimidazo(4,5-b)pyridine-DNA adduct 12%
• Diet 8%
• Food Additives 8%
• Cytochrome P-450 CYP1A2 8%
• Cytochrome P-450 CYP1A1 7%
• Demethylation 7%
• Enzymes 6%
• Lung 6%
• Carcinogens 6%
• Colon 5%
• Water 4%
• Liver 3%