TY - JOUR
T1 - Inter-comparison of boron concentration measurements at INFN-University of Pavia (Italy) and CNEA (Argentina)
AU - Portu, Agustina
AU - Postuma, Ian
AU - Gadan, Mario Alberto
AU - Saint Martin, Gisela
AU - Olivera, María Silvina
AU - Altieri, Saverio
AU - Protti, Nicoletta
AU - Bortolussi, Silva
N1 - Funding Information:
The authors gratefully acknowledge Dr. C. Ferrari and coworkers (University of Pavia) for providing the biological samples, and Dr. L. Ciani and S. Ristori (University of Florence) and Dr. L. Panza (University of Eastern Peiedemont) for providing liposomes and LCOB, respectively. The authors are also grateful to Lic. Silvia Thorp, Paula Curotto and Lic. Emiliano Pozzi for sample irradiation at the RA-3 reactor (CNEA, Buenos Aires) and LENA staff for the irradiations at TRIGA reactor (University of Pavia). We want to especially acknowledge Dr. A. Schwint and her group (CNEA, Buenos Aires) for encouraging this work and for the effort devoted to the inter-comparison. This work was partially funded by National Institute of Nuclear Physics (INFN).
Publisher Copyright:
© 2015 Elsevier Ltd.
PY - 2015/11/1
Y1 - 2015/11/1
N2 - An inter-comparison of three boron determination techniques was carried out between laboratories from INFN-University of Pavia (Italy) and CNEA (Argentina): alpha spectrometry (alpha-spect), neutron capture radiography (NCR) and quantitative autoradiography (QTA). Samples of different nature were analysed: liquid standards, liver homogenates and tissue samples from different treatment protocols. The techniques showed a good agreement in a concentration range of interest in BNCT (1-100. ppm), thus demonstrating their applicability as precise methods to quantify boron and determine its distribution in tissues.
AB - An inter-comparison of three boron determination techniques was carried out between laboratories from INFN-University of Pavia (Italy) and CNEA (Argentina): alpha spectrometry (alpha-spect), neutron capture radiography (NCR) and quantitative autoradiography (QTA). Samples of different nature were analysed: liquid standards, liver homogenates and tissue samples from different treatment protocols. The techniques showed a good agreement in a concentration range of interest in BNCT (1-100. ppm), thus demonstrating their applicability as precise methods to quantify boron and determine its distribution in tissues.
KW - Alpha spectrometry
KW - BNCT
KW - Boron imaging
KW - Boron measurements
KW - Inter-comparison
KW - Neutron autoradiography
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U2 - 10.1016/j.apradiso.2015.07.022
DO - 10.1016/j.apradiso.2015.07.022
M3 - Article
C2 - 26454177
AN - SCOPUS:84943605017
SN - 0969-8043
VL - 105
SP - 35
EP - 39
JO - Applied Radiation and Isotopes
JF - Applied Radiation and Isotopes
ER -