TY - JOUR
T1 - Intermediate water on calcium phosphate minerals
T2 - ITS origin and role in crystal growth
AU - Okada, Masahiro
AU - Hara, Emilio Satoshi
AU - Kobayashi, Daisuke
AU - Kai, Shoki
AU - Ogura, Keiko
AU - Tanaka, Masaru
AU - Matsumoto, Takuya
N1 - Funding Information:
This work was supported in part by Japan Society for the Promotion of Science KAKENHI Grant Nos. JP15K15723, JP25293402, and JP18H05254, and by the Matching Planner Program (MP27115663113) from Japan Science and Technology Agency.
Funding Information:
*E-mail: tmatsu@md.okayama-u.ac.jp. ORCID Masahiro Okada: 0000-0001-9441-3284 Emilio Satoshi Hara: 0000-0001-7374-3487 Masaru Tanaka: 0000-0002-1115-2080 Takuya Matsumoto: 0000-0002-9804-4786 Funding This work was supported in part by Japan Society for the Promotion of Science KAKENHI Grant Nos. JP15K15723, JP25293402, and JP18H05254, and by the Matching Planner Program (MP27115663113) from Japan Science and Technology Agency. Notes The authors declare no competing financial interest.
Publisher Copyright:
© 2019 American Chemical Society
PY - 2019/3
Y1 - 2019/3
N2 - Water molecules are known to play crucial roles both in the formation and biological function of materials. Herein, we show the presence of “intermediate water” on an inorganic solid material, hydroxyapatite. In vitro experiments revealed that Mg substitution of apatite significantly enriched the amount of intermediate water, possibly due to the proton transfer to a hydrogen-bonded network of water around HPO42− on divalent-cation-deficient apatite surfaces. The intermediate water formation related to a markedl su ressed rotein adsor tion on a atite Anal sis of bone a atites suggested that the intermediate water on minerals could play crucial roles in regulating crystal growth.
AB - Water molecules are known to play crucial roles both in the formation and biological function of materials. Herein, we show the presence of “intermediate water” on an inorganic solid material, hydroxyapatite. In vitro experiments revealed that Mg substitution of apatite significantly enriched the amount of intermediate water, possibly due to the proton transfer to a hydrogen-bonded network of water around HPO42− on divalent-cation-deficient apatite surfaces. The intermediate water formation related to a markedl su ressed rotein adsor tion on a atite Anal sis of bone a atites suggested that the intermediate water on minerals could play crucial roles in regulating crystal growth.
KW - Bone apatite mineral growth
KW - Differential scanning calorimetry
KW - Infrared spectroscopy
KW - Intermediate water
KW - Water hydrogen-bonded network
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U2 - 10.1021/acsabm.9b00014
DO - 10.1021/acsabm.9b00014
M3 - Article
AN - SCOPUS:85069761845
SN - 2576-6422
VL - 2
SP - 981
EP - 986
JO - ACS Applied Bio Materials
JF - ACS Applied Bio Materials
IS - 3
ER -