TY - JOUR
T1 - Invasive and noninvasive thymoma
T2 - Distinctive CT features
AU - Tomiyama, Noriyuki
AU - Müller, Nestor L.
AU - Ellis, Samantha J.
AU - Cleverley, Joanne R.
AU - Okumura, Meinoshin
AU - Miyoshi, Shinichiro
AU - Kusumoto, Masahiko
AU - Johkoh, Takeshi
AU - Yoshida, Shigeyuki
AU - Mihara, Naoki
AU - Honda, Osamu
AU - Kozuka, Takenori
AU - Hamada, Seiki
AU - Nakamura, Hironobu
PY - 2001
Y1 - 2001
N2 - Purpose: The purpose of this work was to evaluate the CT features of thymoma and to determine the most helpful findings in differentiating invasive from noninvasive thymoma. Method: The CT scans from 27 patients with invasive thymoma and 23 with noninvasive thymoma were independently assessed by two observers without knowledge of their invasiveness. The presence and distribution of various CT findings were independently analyzed. Results: Invasive thymomas were more likely to have lobulated (16/27, 59%) or irregular (6/27, 22%) contours than noninvasive thymomas (8/23, 35% and 1.5/23, 6%. respectively) (p < 0.05). Invasive thymomas had a higher prevalence of low attenuation areas within the tumor (16/27, 60%) than noninvasive thymomas (5/23, 22%) (p < 0.001) as well as foci of calcification (14.5/27, 54% vs. 6/23, 26%; p < 0.01). Conclusion: The presence of lobulated or irregular contour, areas of low attenuation, and multifocal calcification is suggestive of invasive thymoma.
AB - Purpose: The purpose of this work was to evaluate the CT features of thymoma and to determine the most helpful findings in differentiating invasive from noninvasive thymoma. Method: The CT scans from 27 patients with invasive thymoma and 23 with noninvasive thymoma were independently assessed by two observers without knowledge of their invasiveness. The presence and distribution of various CT findings were independently analyzed. Results: Invasive thymomas were more likely to have lobulated (16/27, 59%) or irregular (6/27, 22%) contours than noninvasive thymomas (8/23, 35% and 1.5/23, 6%. respectively) (p < 0.05). Invasive thymomas had a higher prevalence of low attenuation areas within the tumor (16/27, 60%) than noninvasive thymomas (5/23, 22%) (p < 0.001) as well as foci of calcification (14.5/27, 54% vs. 6/23, 26%; p < 0.01). Conclusion: The presence of lobulated or irregular contour, areas of low attenuation, and multifocal calcification is suggestive of invasive thymoma.
KW - Computed tomography
KW - Thymoma
KW - Thymus neoplasms
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U2 - 10.1097/00004728-200105000-00010
DO - 10.1097/00004728-200105000-00010
M3 - Article
C2 - 11351188
AN - SCOPUS:0343774114
SN - 0363-8715
VL - 25
SP - 388
EP - 393
JO - Journal of Computer Assisted Tomography
JF - Journal of Computer Assisted Tomography
IS - 3
ER -