Arenes possessing an N-(quinolin-8-yl)amide directing group are ortho-allylated with allyl phenyl ether in the presence of an iron/diphosphine catalyst and an organometallic base at 50-70 C. The reaction proceeds via fast iron-catalyzed C-H activation, followed by reaction of the resulting iron intermediate with the allyl ether in γ-selective fashion.
|Number of pages||3|
|Journal||Journal of the American Chemical Society|
|Publication status||Published - Nov 27 2013|
ASJC Scopus subject areas
- Colloid and Surface Chemistry