Isolation and structure revision of 10-deacetyltaxinine from the seeds of the Chinese yew, Taxus mairei

Qing Wen Shi; Zuo Ping Li; Ding Zhao; Ji Shun Gu; Hiromasa Kiyota

doi:10.1080/14786410500111184

Isolation and structure revision of 10-deacetyltaxinine from the seeds of the Chinese yew, Taxus mairei

Qing Wen Shi, Zuo Ping Li, Ding Zhao, Ji Shun Gu, Hiromasa Kiyota

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

A new taxoid was isolated from the methanol extract of the seeds of Taxus mairei. Its structures were established as 2α,9α-diacetoxy-10β-hydroxy-5α-cinnamoyloxytaxa -4(20), 1l-dien-13-one (l0-deacetyltaxinine, 1) on the basis of spectral analysis including ¹H-NMR, ¹³C-NMR, HMQC, HMBC, NOESY, and HR-FABMS. The structure of previously reported l0-deacetyltaxinine is 9-deacetyltaxinine.

Original language	English
Pages (from-to)	47-51
Number of pages	5
Journal	Natural Product Research
Volume	20
Issue number	1
DOIs	https://doi.org/10.1080/14786410500111184
Publication status	Published - Jan 2006
Externally published	Yes

Keywords

10-Deacetyltaxinine
Isolation
Seeds
Taxanes
Taxus mairei
Yew

ASJC Scopus subject areas

Analytical Chemistry
Biochemistry
Plant Science
Organic Chemistry

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10.1080/14786410500111184

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title = "Isolation and structure revision of 10-deacetyltaxinine from the seeds of the Chinese yew, Taxus mairei",

abstract = "A new taxoid was isolated from the methanol extract of the seeds of Taxus mairei. Its structures were established as 2α,9α-diacetoxy-10β-hydroxy-5α-cinnamoyloxytaxa -4(20), 1l-dien-13-one (l0-deacetyltaxinine, 1) on the basis of spectral analysis including 1H-NMR, 13C-NMR, HMQC, HMBC, NOESY, and HR-FABMS. The structure of previously reported l0-deacetyltaxinine is 9-deacetyltaxinine.",

keywords = "10-Deacetyltaxinine, Isolation, Seeds, Taxanes, Taxus mairei, Yew",

author = "Shi, {Qing Wen} and Li, {Zuo Ping} and Ding Zhao and Gu, {Ji Shun} and Hiromasa Kiyota",

note = "Funding Information: The Project was sponsored by the Foundation for Researching New Drugs of People{\textquoteright}s Republic of China, No: 2003AA2Z3527, and by the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry of People{\textquoteright}s Republic of China.",

year = "2006",

month = jan,

doi = "10.1080/14786410500111184",

language = "English",

volume = "20",

pages = "47--51",

journal = "Natural Product Research",

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T1 - Isolation and structure revision of 10-deacetyltaxinine from the seeds of the Chinese yew, Taxus mairei

AU - Shi, Qing Wen

AU - Li, Zuo Ping

AU - Zhao, Ding

AU - Gu, Ji Shun

AU - Kiyota, Hiromasa

N1 - Funding Information: The Project was sponsored by the Foundation for Researching New Drugs of People’s Republic of China, No: 2003AA2Z3527, and by the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry of People’s Republic of China.

PY - 2006/1

Y1 - 2006/1

N2 - A new taxoid was isolated from the methanol extract of the seeds of Taxus mairei. Its structures were established as 2α,9α-diacetoxy-10β-hydroxy-5α-cinnamoyloxytaxa -4(20), 1l-dien-13-one (l0-deacetyltaxinine, 1) on the basis of spectral analysis including 1H-NMR, 13C-NMR, HMQC, HMBC, NOESY, and HR-FABMS. The structure of previously reported l0-deacetyltaxinine is 9-deacetyltaxinine.

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KW - 10-Deacetyltaxinine

KW - Isolation

KW - Seeds

KW - Taxanes

KW - Taxus mairei

KW - Yew

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Isolation and structure revision of 10-deacetyltaxinine from the seeds of the Chinese yew, Taxus mairei

Abstract

Keywords

ASJC Scopus subject areas

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