Ketogenic diet therapy is effective in encephalitis with refractory seizures

Kosuke Matsuzono, Tomoko Kurata, Shoko Deguchi, Toru Yamashita, Kentaro Deguchi, Koji Abe

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


Objective and importance: Although ketogenic diet therapy is effective in refractory seizures in childhood, its effect on adult encephalitis with similar refractory seizures and prolonged encephalopathy has not been well reported. Clinical presentation: We report here a case of a 22-year-old man with acute encephalitis with refractory repetitive partial seizures (AERRPS). Intervention: Partial seizures of the face developed to repeated generalized convulsions, which were refractory against anti-epileptic drugs and a high dose of propofol. After struggling for 9 months, he dramatically recovered after ketogenic diet therapy. Conclusion: Ketogenic diet therapy may be an important tool to help cure AERRPS.

Original languageEnglish
Pages (from-to)906-910
Number of pages5
JournalNeurological Research
Issue number10
Publication statusPublished - Oct 1 2014


  • Encephalitis
  • Ketogenic diet therapy
  • Refractory seizures
  • SPECT with <sup>123</sup>I-iomazenil

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


Dive into the research topics of 'Ketogenic diet therapy is effective in encephalitis with refractory seizures'. Together they form a unique fingerprint.

Cite this