Laparoscopic Hepatectomy for the Patient with Hemophilia A with High Titer Factor VIII Inhibitor

Tatsuo Matsuda; Yuzo Umeda; Kazuhiro Yoshida; Tadakazu Matsuda; Masatoshi Uno; Masaya Abe; Noboru Asada; Yoshinobu Maeda; Takahito Yagi; Toshiyoshi Fujiwara

Laparoscopic Hepatectomy for the Patient with Hemophilia A with High Titer Factor VIII Inhibitor

Tatsuo Matsuda, Yuzo Umeda, Kazuhiro Yoshida, Tadakazu Matsuda, Masatoshi Uno, Masaya Abe, Noboru Asada, Yoshinobu Maeda, Takahito Yagi, Toshiyoshi Fujiwara

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

We present the first case of laparoscopic left lateral segmentectomy for hepatocellular carcinoma (HCC) in a patient with hemophilia A, acquired hepatitis C, and high-titer factor VIII inhibitor, which was confirmed by preoperative diagnosis. He underwent laparoscopic left lateral segmentectomy with the administration of recombinant activated factor VII. Surgery could be performed with reduced intraoperative hemorrhage. He experienced postoperative intra-abdominal wall hemorrhage, which was successfully managed with red cell concentrates transfusion and administration of recombinant activated factor VII. Laparoscopic hepatectomy can be applied for hemophilia patients with high titer inhibitors.

Original language	English
Pages (from-to)	199-204
Number of pages	6
Journal	Acta medica Okayama
Volume	75
Issue number	2
Publication status	Published - 2021

Keywords

hemophilia A
hepatectomy
hepatocellular carcinoma
inhibitor
laparoscopy

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Laparoscopic Hepatectomy for the Patient with Hemophilia A with High Titer Factor VIII Inhibitor",

abstract = "We present the first case of laparoscopic left lateral segmentectomy for hepatocellular carcinoma (HCC) in a patient with hemophilia A, acquired hepatitis C, and high-titer factor VIII inhibitor, which was confirmed by preoperative diagnosis. He underwent laparoscopic left lateral segmentectomy with the administration of recombinant activated factor VII. Surgery could be performed with reduced intraoperative hemorrhage. He experienced postoperative intra-abdominal wall hemorrhage, which was successfully managed with red cell concentrates transfusion and administration of recombinant activated factor VII. Laparoscopic hepatectomy can be applied for hemophilia patients with high titer inhibitors.",

keywords = "hemophilia A, hepatectomy, hepatocellular carcinoma, inhibitor, laparoscopy",

author = "Tatsuo Matsuda and Yuzo Umeda and Kazuhiro Yoshida and Tadakazu Matsuda and Masatoshi Uno and Masaya Abe and Noboru Asada and Yoshinobu Maeda and Takahito Yagi and Toshiyoshi Fujiwara",

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T1 - Laparoscopic Hepatectomy for the Patient with Hemophilia A with High Titer Factor VIII Inhibitor

AU - Matsuda, Tatsuo

AU - Umeda, Yuzo

AU - Yoshida, Kazuhiro

AU - Matsuda, Tadakazu

AU - Uno, Masatoshi

AU - Abe, Masaya

AU - Asada, Noboru

AU - Maeda, Yoshinobu

AU - Yagi, Takahito

AU - Fujiwara, Toshiyoshi

PY - 2021

Y1 - 2021

N2 - We present the first case of laparoscopic left lateral segmentectomy for hepatocellular carcinoma (HCC) in a patient with hemophilia A, acquired hepatitis C, and high-titer factor VIII inhibitor, which was confirmed by preoperative diagnosis. He underwent laparoscopic left lateral segmentectomy with the administration of recombinant activated factor VII. Surgery could be performed with reduced intraoperative hemorrhage. He experienced postoperative intra-abdominal wall hemorrhage, which was successfully managed with red cell concentrates transfusion and administration of recombinant activated factor VII. Laparoscopic hepatectomy can be applied for hemophilia patients with high titer inhibitors.

AB - We present the first case of laparoscopic left lateral segmentectomy for hepatocellular carcinoma (HCC) in a patient with hemophilia A, acquired hepatitis C, and high-titer factor VIII inhibitor, which was confirmed by preoperative diagnosis. He underwent laparoscopic left lateral segmentectomy with the administration of recombinant activated factor VII. Surgery could be performed with reduced intraoperative hemorrhage. He experienced postoperative intra-abdominal wall hemorrhage, which was successfully managed with red cell concentrates transfusion and administration of recombinant activated factor VII. Laparoscopic hepatectomy can be applied for hemophilia patients with high titer inhibitors.

KW - hemophilia A

KW - hepatectomy

KW - hepatocellular carcinoma

KW - inhibitor

KW - laparoscopy

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JF - Acta medica Okayama

IS - 2

ER -

Laparoscopic Hepatectomy for the Patient with Hemophilia A with High Titer Factor VIII Inhibitor

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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