Liquid-Liquid Phase Transition Drives Intra-chloroplast Cargo Sorting

Min Ouyang, Xiaoyi Li, Jing Zhang, Peiqiang Feng, Hua Pu, Lingxi Kong, Zechen Bai, Liwei Rong, Xiumei Xu, Wei Chi, Qiang Wang, Fan Chen, Congming Lu, Jianren Shen, Lixin Zhang

Research output: Contribution to journalArticlepeer-review

49 Citations (Scopus)


A pair of ankyrin repeat proteins in chloroplasts recognizes signal peptides on thylakoid-bound cargo proteins and undergoes liquid-liquid phase separation to facilitate their sorting and transport.

Original languageEnglish
Pages (from-to)1144-1159.e20
Issue number6
Publication statusPublished - Mar 19 2020


  • ankyrin-repeat proteins
  • cargo sorting
  • chloroplast
  • intrinsically disordered regions
  • liquid-liquid phase separation
  • nuclear-encoded chloroplast proteins
  • thylakoid membranes
  • twin arginine translocation pathway

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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