TY - JOUR
T1 - Lumped parameter model for hemodynamic simulation of congenital heart diseases
AU - Shimizu, Shuji
AU - Une, Dai
AU - Kawada, Toru
AU - Hayama, Yohsuke
AU - Kamiya, Atsunori
AU - Shishido, Toshiaki
AU - Sugimachi, Masaru
N1 - Publisher Copyright:
© 2017, The Physiological Society of Japan and Springer Japan KK, part of Springer Nature.
PY - 2018/3/1
Y1 - 2018/3/1
N2 - The recent development of computer technology has made it possible to simulate the hemodynamics of congenital heart diseases on a desktop computer. However, multi-scale modeling of the cardiovascular system based on computed tomographic and magnetic resonance images still requires long simulation times. The lumped parameter model is potentially beneficial for real-time bedside simulation of congenital heart diseases. In this review, we introduce the basics of the lumped parameter model (time-varying elastance chamber model combined with modified Windkessel vasculature model) and illustrate its usage in hemodynamic simulation of congenital heart diseases using examples such as hypoplastic left heart syndrome and Fontan circulation. We also discuss the advantages of the lumped parameter model and the problems for clinical use.
AB - The recent development of computer technology has made it possible to simulate the hemodynamics of congenital heart diseases on a desktop computer. However, multi-scale modeling of the cardiovascular system based on computed tomographic and magnetic resonance images still requires long simulation times. The lumped parameter model is potentially beneficial for real-time bedside simulation of congenital heart diseases. In this review, we introduce the basics of the lumped parameter model (time-varying elastance chamber model combined with modified Windkessel vasculature model) and illustrate its usage in hemodynamic simulation of congenital heart diseases using examples such as hypoplastic left heart syndrome and Fontan circulation. We also discuss the advantages of the lumped parameter model and the problems for clinical use.
KW - Congenital heart diseases
KW - Hemodynamic simulation
KW - Lumped parameter model
KW - Time-varying elastance
KW - Windkessel model
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U2 - 10.1007/s12576-017-0585-1
DO - 10.1007/s12576-017-0585-1
M3 - Review article
C2 - 29270856
AN - SCOPUS:85038619703
SN - 1880-6546
VL - 68
SP - 103
EP - 111
JO - Journal of Physiological Sciences
JF - Journal of Physiological Sciences
IS - 2
ER -