Lung transplantation in rats

Tomohiro Kawamura; Yugo Tanaka; Norihisa Shigemura; Yoshiya Toyoda; Atsunori Nakao

Lung transplantation in rats

Tomohiro Kawamura, Yugo Tanaka, Norihisa Shigemura, Yoshiya Toyoda, Atsunori Nakao

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This chapter describes a unilateral, orthotopic lung transplantation (LTx) model using the cuff technique in rats. The advantage of this model over the suture technique includes a decrease in operation time, prevention of bleeding from the vascular anastomosis site, and shorter training period with stable outcomes. The rat LTx model has been proven valid for understanding physiological/pathological events occurring in lung grafts, as well as evaluating graft injuries due to inflammation or rejection, as seen in clinical lung transplant.& copy 2013 Nova Science Publishers, Inc.

Original language	English
Title of host publication	Experimental Organ Transplantation
Publisher	Nova Science Publishers, Inc.
Pages	159-173
Number of pages	15
ISBN (Print)	9781624179495
Publication status	Published - Dec 1 2013
Externally published	Yes

Keywords

Allograft rejection
Cuff technique
Ischemia/reperfusion injury
Non-suturing anastomosis
Orthotopic rat lung transplantation

ASJC Scopus subject areas

Medicine(all)

Cite this

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AU - Kawamura, Tomohiro

AU - Tanaka, Yugo

AU - Shigemura, Norihisa

AU - Toyoda, Yoshiya

AU - Nakao, Atsunori

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Y1 - 2013/12/1

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AB - This chapter describes a unilateral, orthotopic lung transplantation (LTx) model using the cuff technique in rats. The advantage of this model over the suture technique includes a decrease in operation time, prevention of bleeding from the vascular anastomosis site, and shorter training period with stable outcomes. The rat LTx model has been proven valid for understanding physiological/pathological events occurring in lung grafts, as well as evaluating graft injuries due to inflammation or rejection, as seen in clinical lung transplant.& copy 2013 Nova Science Publishers, Inc.

KW - Allograft rejection

KW - Cuff technique

KW - Ischemia/reperfusion injury

KW - Non-suturing anastomosis

KW - Orthotopic rat lung transplantation

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M3 - Chapter

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SP - 159

EP - 173

BT - Experimental Organ Transplantation

PB - Nova Science Publishers, Inc.

ER -

Lung transplantation in rats

Abstract

Keywords

ASJC Scopus subject areas

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