Abstract
We construct Lyapunov functionals for delay differential equation models of infectious diseases in vivo to analyze the stability of the equilibria. The Lyapunov functionals contain the terms that integrate over all previous states. An appropriate evaluation of the logarithm functions in those terms guarantees the existence of the integrals. We apply the rigorous analysis for the one-strain models to multistrain models by using mathematical induction.
Original language | English |
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Pages (from-to) | 507-536 |
Number of pages | 30 |
Journal | Discrete and Continuous Dynamical Systems - Series B |
Volume | 22 |
Issue number | 2 |
DOIs | |
Publication status | Published - Mar 2017 |
Keywords
- Delay differential equation
- Global stability
- Infinitely distributed delay
- Lyapunov functional
- Multistrain
- Virus-immune model
ASJC Scopus subject areas
- Discrete Mathematics and Combinatorics
- Applied Mathematics