Lycopladine H, a novel alkaloid with fused-tetracyclic skeleton from Lycopodium complanatum

Kan'Ichiro Ishiuchi; Takaaki Kubota; Shigeki Hayashi; Toshiro Shibata; Jun'Ichi Kobayashi

doi:10.1016/j.tetlet.2009.09.035

Lycopladine H, a novel alkaloid with fused-tetracyclic skeleton from Lycopodium complanatum

Kan'Ichiro Ishiuchi, Takaaki Kubota, Shigeki Hayashi, Toshiro Shibata, Jun'Ichi Kobayashi

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

A novel Lycopodium alkaloid, lycopladine H (1), with a fused-tetracyclic ring system consisting of an azocane ring connected to a [2,2,2]-bicyclooctane ring and a 3-piperidone ring, was isolated from the club moss Lycopodium complanatum. The structure and relative stereochemistry of 1 were elucidated on the basis of spectroscopic data.

Original language	English
Pages (from-to)	6534-6536
Number of pages	3
Journal	Tetrahedron Letters
Volume	50
Issue number	47
DOIs	https://doi.org/10.1016/j.tetlet.2009.09.035
Publication status	Published - Nov 25 2009
Externally published	Yes

Keywords

Lycopladine H
Lycopodium alkaloid
Lycopodium complanatum

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2009.09.035

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title = "Lycopladine H, a novel alkaloid with fused-tetracyclic skeleton from Lycopodium complanatum",

abstract = "A novel Lycopodium alkaloid, lycopladine H (1), with a fused-tetracyclic ring system consisting of an azocane ring connected to a [2,2,2]-bicyclooctane ring and a 3-piperidone ring, was isolated from the club moss Lycopodium complanatum. The structure and relative stereochemistry of 1 were elucidated on the basis of spectroscopic data.",

keywords = "Lycopladine H, Lycopodium alkaloid, Lycopodium complanatum",

author = "Kan'Ichiro Ishiuchi and Takaaki Kubota and Shigeki Hayashi and Toshiro Shibata and Jun'Ichi Kobayashi",

note = "Funding Information: The authors thank Ms. S. Oka, Equipment Management Center, Hokkaido University, for measurements of ESIMS. This work was partly supported by a research fellowship for young scientists from the Japan Society for the Promotion of Science (to K.I.), and a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan.",

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doi = "10.1016/j.tetlet.2009.09.035",

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journal = "Tetrahedron Letters",

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T1 - Lycopladine H, a novel alkaloid with fused-tetracyclic skeleton from Lycopodium complanatum

AU - Ishiuchi, Kan'Ichiro

AU - Kubota, Takaaki

AU - Hayashi, Shigeki

AU - Shibata, Toshiro

AU - Kobayashi, Jun'Ichi

N1 - Funding Information: The authors thank Ms. S. Oka, Equipment Management Center, Hokkaido University, for measurements of ESIMS. This work was partly supported by a research fellowship for young scientists from the Japan Society for the Promotion of Science (to K.I.), and a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan.

PY - 2009/11/25

Y1 - 2009/11/25

N2 - A novel Lycopodium alkaloid, lycopladine H (1), with a fused-tetracyclic ring system consisting of an azocane ring connected to a [2,2,2]-bicyclooctane ring and a 3-piperidone ring, was isolated from the club moss Lycopodium complanatum. The structure and relative stereochemistry of 1 were elucidated on the basis of spectroscopic data.

AB - A novel Lycopodium alkaloid, lycopladine H (1), with a fused-tetracyclic ring system consisting of an azocane ring connected to a [2,2,2]-bicyclooctane ring and a 3-piperidone ring, was isolated from the club moss Lycopodium complanatum. The structure and relative stereochemistry of 1 were elucidated on the basis of spectroscopic data.

KW - Lycopladine H

KW - Lycopodium alkaloid

KW - Lycopodium complanatum

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DO - 10.1016/j.tetlet.2009.09.035

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 47

ER -

Lycopladine H, a novel alkaloid with fused-tetracyclic skeleton from Lycopodium complanatum

Abstract

Keywords

ASJC Scopus subject areas

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