Macromolecular insect chitinase inhibitors produced by fungi: Screening and partial characterization

Teruhiko Nitoda, Hirokazu Usuki, Atsushi Kurata, Hiroshi Kanzaki

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Culture broths of fungal strains were screened for novel insect chitinase inhibitors using the Spodoptera litura chitinase inhibitory assay. The culture filtrates of 5 strains showed potent and specific inhibitory activity against the insect chitinase. Partial characterization showed that the active compounds produced by these strains were water-soluble macromolecular compounds which had not been hitherto reported as chitinase inhibitors. These novel chitinase inhibitors are, therefore, expected to be potential agents for insect control.

Original languageEnglish
Pages (from-to)33-36
Number of pages4
JournalJournal of Pesticide Sciences
Issue number1
Publication statusPublished - 2003


  • Insect chitinase inhibitor
  • Insect growth regulator
  • Polysaccharide
  • Protein
  • Spodoptera litura
  • Static culture

ASJC Scopus subject areas

  • Insect Science
  • Health, Toxicology and Mutagenesis


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