Manganese-catalyzed insertion of aldehydes into a C-H bond

Yoichiro Kuninobu; Yuta Nishina; Takahiro Takeuchi; Kazuhiko Takai

doi:10.1002/anie.200702256

Manganese-catalyzed insertion of aldehydes into a C-H bond

Yoichiro Kuninobu, Yuta Nishina, Takahiro Takeuchi, Kazuhiko Takai

Research Core for Interdisciplinary Sciences

Research output: Contribution to journal › Article › peer-review

193 Citations (Scopus)

Abstract

(Chemical Equation Presented) Mn gets in the game: In the presence of a manganese catalyst and a stoichiometric amount of hydrosilane, aldehydes insert into C-H bonds of aromatic rings of compounds with directing groups (see scheme). This first example of a manganese-catalyzed chemical transformation through C-H bond activation gives silyl ethers in good to excellent yields and can also be applied to asymmetric transformation.

Original language	English
Pages (from-to)	6518-6520
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	46
Issue number	34
DOIs	https://doi.org/10.1002/anie.200702256
Publication status	Published - 2007

Keywords

Aldehydes
Asymmetric synthesis
C-H activation
Manganese
Silyl ethers

ASJC Scopus subject areas

Catalysis
Chemistry(all)

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10.1002/anie.200702256

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AU - Kuninobu, Yoichiro

AU - Nishina, Yuta

AU - Takeuchi, Takahiro

AU - Takai, Kazuhiko

PY - 2007

Y1 - 2007

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AB - (Chemical Equation Presented) Mn gets in the game: In the presence of a manganese catalyst and a stoichiometric amount of hydrosilane, aldehydes insert into C-H bonds of aromatic rings of compounds with directing groups (see scheme). This first example of a manganese-catalyzed chemical transformation through C-H bond activation gives silyl ethers in good to excellent yields and can also be applied to asymmetric transformation.

KW - Aldehydes

KW - Asymmetric synthesis

KW - C-H activation

KW - Manganese

KW - Silyl ethers

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Manganese-catalyzed insertion of aldehydes into a C-H bond

Abstract

Keywords

ASJC Scopus subject areas

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