TY - JOUR
T1 - Massive bleeding from acute multiple nonspecific ulcer of the small intestine after R-CHOP with a diffuse large B-cell lymphoma
T2 - A rare case report
AU - Kato, Kazuya
AU - Nagase, Atsushi
AU - Onodera, Kazuhiko
AU - Matsuda, Minoru
AU - Kato, Yurina
AU - Kato, Kimitaka
AU - Kawakami, Takako
AU - Higuchi, Mineko
AU - Iwasaki, Yoshiaki
AU - Taniguchi, Masahiko
AU - Furukawa, Hiroyuki
PY - 2011/12/27
Y1 - 2011/12/27
N2 - Background: The small intestine between the second part of the duodenum and ileocecal valves is an uncommon site for hemorrhage. Ulcers of the small intestine are rare and in most cases are caused by infections, inflammatory bowel diseases, malignancies or drugs. Ulcers of the small intestine are sometimes associated with massive, life-threatening hemorrhage and are difficult to diagnose. Case Report: We report a case of acute, massive bleeding from multiple small-bowel ulcers in a 78-year-old woman with malignant lymphoma (diffuse large B-cell lymphoma) after R-CHOP (cyclophosphamide, vincristine, doxorubicine, prednisolone and rituximab) therapy. Conclusions: The current report describes a rare case of acute, multiple, nonspecific small intestine ulcers associated with massive gastrointestinal bleeding and presents a review of the literature.
AB - Background: The small intestine between the second part of the duodenum and ileocecal valves is an uncommon site for hemorrhage. Ulcers of the small intestine are rare and in most cases are caused by infections, inflammatory bowel diseases, malignancies or drugs. Ulcers of the small intestine are sometimes associated with massive, life-threatening hemorrhage and are difficult to diagnose. Case Report: We report a case of acute, massive bleeding from multiple small-bowel ulcers in a 78-year-old woman with malignant lymphoma (diffuse large B-cell lymphoma) after R-CHOP (cyclophosphamide, vincristine, doxorubicine, prednisolone and rituximab) therapy. Conclusions: The current report describes a rare case of acute, multiple, nonspecific small intestine ulcers associated with massive gastrointestinal bleeding and presents a review of the literature.
KW - CMUSE (cryptogenic multifocal ulcerous stenosing enteritis)
KW - Malignant lymphoma (diffuse large B-cell lymphoma, DLBCL))
KW - Massive gastrointestinal bleeding
KW - Nonspecific multiple ulcer
KW - R-CHOP therapy
KW - Small intestine (jejunum, ileum)
KW - Thyroid gland
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U2 - 10.12659/AJCR.882207
DO - 10.12659/AJCR.882207
M3 - Review article
AN - SCOPUS:84863398432
SN - 1941-5923
VL - 12
SP - 198
EP - 202
JO - American Journal of Case Reports
JF - American Journal of Case Reports
M1 - 5
ER -