Maternal smoking as a risk factor for childhood intussusception

Yasuo Nakahara, Takashi Yorifuji, Toshihide Kubo, Hiroyuki Doi

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


Risk factors for intussusception have only rarely been reported. We examined the association between the risk of hospital admission for intussusception and maternal smoking, using a nationwide population-based longitudinal survey begun in Japan in 2010. Maternal smoking status was queried at 6 months of age, and responses to questions at 18 months of age about history of hospitalization for intussusception during the previous year were used as an outcome of interest. We conducted logistic regression analyses controlling for potential confounding factors. Maternal smoking increased the risk of hospitalization for intussusception (adjusted OR = 2.75, 95% CI [1.09, 6.96]) compared with not smoking, and a dose-response relationship was observed for the association. Maternal smoking is associated with an increased risk of intussusception development in children between the ages of 6 and 18 months.

Original languageEnglish
Pages (from-to)96-101
Number of pages6
JournalArchives of Environmental and Occupational Health
Issue number2
Publication statusPublished - Mar 4 2018


  • Children
  • epidemiology
  • intussusception
  • maternal smoking

ASJC Scopus subject areas

  • Toxicology
  • Environmental Science(all)
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis


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