Measurement of lumbar spinal bone mineral density in preterm infants by dual-energy x-ray absorptiometry

Hirokazu Tsukahara; Masakatsu Sudo; Minoru Umezaki; Yasushi Fujii; Masanori Kuriyama; Kazutaka Yamamoto; Yasushi Ishii

doi:10.1159/000243978

Measurement of lumbar spinal bone mineral density in preterm infants by dual-energy x-ray absorptiometry

Hirokazu Tsukahara, Masakatsu Sudo, Minoru Umezaki, Yasushi Fujii, Masanori Kuriyama, Kazutaka Yamamoto, Yasushi Ishii

Research output: Contribution to journal › Article › peer-review

50 Citations (Scopus)

Abstract

Lumbar spinal bone mineral density (BMD) was measured in 40 preterm infants by dual-energy X-ray absorptiometry (DXA). During the first several months of life, their BMD was considerably lower than that of normal term infants and the osteopenia was more pronounced in the more preterm and smaller infants. Weak (inverse) correlations were found be-tween the BMD and urinary calcium/creatinine or tubular phosphorus reabsorption ratio. Rickets-like changes in the forearm bones did not predict the greater spinal osteopenia. Follow-up study was performed in 10 preterms. In 3 of the 4 who underwent the last DXA between 8 and 12 months, BMD had improved remarkably. Our present study shows the potential of DXA for the assessment and management of osteopenia of prematurity.

Original language	English
Pages (from-to)	96-103
Number of pages	8
Journal	Neonatology
Volume	64
Issue number	2-3
DOIs	https://doi.org/10.1159/000243978
Publication status	Published - 1993
Externally published	Yes

Keywords

Bone mineral density
Dual-energy X-ray absorptiometry
Lumbar spine
Osteopenia of prematurity
Preterm infants

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Developmental Biology

Access to Document

10.1159/000243978

Cite this

@article{5533cf3ca689471f843bf97f441f5130,

title = "Measurement of lumbar spinal bone mineral density in preterm infants by dual-energy x-ray absorptiometry",

abstract = "Lumbar spinal bone mineral density (BMD) was measured in 40 preterm infants by dual-energy X-ray absorptiometry (DXA). During the first several months of life, their BMD was considerably lower than that of normal term infants and the osteopenia was more pronounced in the more preterm and smaller infants. Weak (inverse) correlations were found be-tween the BMD and urinary calcium/creatinine or tubular phosphorus reabsorption ratio. Rickets-like changes in the forearm bones did not predict the greater spinal osteopenia. Follow-up study was performed in 10 preterms. In 3 of the 4 who underwent the last DXA between 8 and 12 months, BMD had improved remarkably. Our present study shows the potential of DXA for the assessment and management of osteopenia of prematurity.",

keywords = "Bone mineral density, Dual-energy X-ray absorptiometry, Lumbar spine, Osteopenia of prematurity, Preterm infants",

author = "Hirokazu Tsukahara and Masakatsu Sudo and Minoru Umezaki and Yasushi Fujii and Masanori Kuriyama and Kazutaka Yamamoto and Yasushi Ishii",

year = "1993",

doi = "10.1159/000243978",

language = "English",

volume = "64",

pages = "96--103",

journal = "Neonatology",

issn = "1661-7800",

publisher = "S. Karger AG",

number = "2-3",

}

TY - JOUR

T1 - Measurement of lumbar spinal bone mineral density in preterm infants by dual-energy x-ray absorptiometry

AU - Tsukahara, Hirokazu

AU - Sudo, Masakatsu

AU - Umezaki, Minoru

AU - Fujii, Yasushi

AU - Kuriyama, Masanori

AU - Yamamoto, Kazutaka

AU - Ishii, Yasushi

PY - 1993

Y1 - 1993

N2 - Lumbar spinal bone mineral density (BMD) was measured in 40 preterm infants by dual-energy X-ray absorptiometry (DXA). During the first several months of life, their BMD was considerably lower than that of normal term infants and the osteopenia was more pronounced in the more preterm and smaller infants. Weak (inverse) correlations were found be-tween the BMD and urinary calcium/creatinine or tubular phosphorus reabsorption ratio. Rickets-like changes in the forearm bones did not predict the greater spinal osteopenia. Follow-up study was performed in 10 preterms. In 3 of the 4 who underwent the last DXA between 8 and 12 months, BMD had improved remarkably. Our present study shows the potential of DXA for the assessment and management of osteopenia of prematurity.

AB - Lumbar spinal bone mineral density (BMD) was measured in 40 preterm infants by dual-energy X-ray absorptiometry (DXA). During the first several months of life, their BMD was considerably lower than that of normal term infants and the osteopenia was more pronounced in the more preterm and smaller infants. Weak (inverse) correlations were found be-tween the BMD and urinary calcium/creatinine or tubular phosphorus reabsorption ratio. Rickets-like changes in the forearm bones did not predict the greater spinal osteopenia. Follow-up study was performed in 10 preterms. In 3 of the 4 who underwent the last DXA between 8 and 12 months, BMD had improved remarkably. Our present study shows the potential of DXA for the assessment and management of osteopenia of prematurity.

KW - Bone mineral density

KW - Dual-energy X-ray absorptiometry

KW - Lumbar spine

KW - Osteopenia of prematurity

KW - Preterm infants

UR - http://www.scopus.com/inward/record.url?scp=0027507812&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027507812&partnerID=8YFLogxK

U2 - 10.1159/000243978

DO - 10.1159/000243978

M3 - Article

C2 - 8260552

AN - SCOPUS:0027507812

SN - 1661-7800

VL - 64

SP - 96

EP - 103

JO - Neonatology

JF - Neonatology

IS - 2-3

ER -

Measurement of lumbar spinal bone mineral density in preterm infants by dual-energy x-ray absorptiometry

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this