Measurement of pH in fluidic chip using a terahertz chemical microscope

Toshihiko Kiwa; Shohei Oka; Yuji Minami; Iwao Kawayama; Masayoshi Tonouchi; Keiji Tsukada

doi:10.1541/ieejsmas.129.221

Measurement of pH in fluidic chip using a terahertz chemical microscope

Toshihiko Kiwa, Shohei Oka, Yuji Minami, Iwao Kawayama, Masayoshi Tonouchi, Keiji Tsukada

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

A terahertz chemical microscope (TCM) has been developed to visualize the chemical concentration of solutions in fluidic chips. Chemical potential-terahertz transducers were newly developed and applied to the bottom surfaces of the flow channels. When femtosecond laser pulses hit the transducers, terahertz waves are radiated from them. Since the amplitude of terahertz waves can be related to the chemical potential on the surface of the device, the distribution of chemical reactions on the surface can be visualized by scanning the laser on the device. Here, we report the demonstration of mapping of pH values using TCM with a spatial resolution of less than 1 mm. The pH distribution of the flow channels filled with 0.01 M NaOH and HC1 was successfully visualized. In addition, the neutralization process was monitored.

Original language	English
Pages (from-to)	221-224
Number of pages	4
Journal	IEEJ Transactions on Sensors and Micromachines
Volume	129
Issue number	7
DOIs	https://doi.org/10.1541/ieejsmas.129.221
Publication status	Published - Sept 25 2009

Keywords

Chemical potential
Femtosecond laser
Fluidic chip
PH detection
Terahertz

ASJC Scopus subject areas

Mechanical Engineering
Electrical and Electronic Engineering

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10.1541/ieejsmas.129.221

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title = "Measurement of pH in fluidic chip using a terahertz chemical microscope",

abstract = "A terahertz chemical microscope (TCM) has been developed to visualize the chemical concentration of solutions in fluidic chips. Chemical potential-terahertz transducers were newly developed and applied to the bottom surfaces of the flow channels. When femtosecond laser pulses hit the transducers, terahertz waves are radiated from them. Since the amplitude of terahertz waves can be related to the chemical potential on the surface of the device, the distribution of chemical reactions on the surface can be visualized by scanning the laser on the device. Here, we report the demonstration of mapping of pH values using TCM with a spatial resolution of less than 1 mm. The pH distribution of the flow channels filled with 0.01 M NaOH and HC1 was successfully visualized. In addition, the neutralization process was monitored.",

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AU - Kiwa, Toshihiko

AU - Oka, Shohei

AU - Minami, Yuji

AU - Kawayama, Iwao

AU - Tonouchi, Masayoshi

AU - Tsukada, Keiji

PY - 2009/9/25

Y1 - 2009/9/25

N2 - A terahertz chemical microscope (TCM) has been developed to visualize the chemical concentration of solutions in fluidic chips. Chemical potential-terahertz transducers were newly developed and applied to the bottom surfaces of the flow channels. When femtosecond laser pulses hit the transducers, terahertz waves are radiated from them. Since the amplitude of terahertz waves can be related to the chemical potential on the surface of the device, the distribution of chemical reactions on the surface can be visualized by scanning the laser on the device. Here, we report the demonstration of mapping of pH values using TCM with a spatial resolution of less than 1 mm. The pH distribution of the flow channels filled with 0.01 M NaOH and HC1 was successfully visualized. In addition, the neutralization process was monitored.

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KW - Femtosecond laser

KW - Fluidic chip

KW - PH detection

KW - Terahertz

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Measurement of pH in fluidic chip using a terahertz chemical microscope

Abstract

Keywords

ASJC Scopus subject areas

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