TY - JOUR
T1 - Mechanosensory trichome cells evoke a mechanical stimuli–induced immune response in Arabidopsis thaliana
AU - Matsumura, Mamoru
AU - Nomoto, Mika
AU - Itaya, Tomotaka
AU - Aratani, Yuri
AU - Iwamoto, Mizuki
AU - Matsuura, Takakazu
AU - Hayashi, Yuki
AU - Mori, Tsuyoshi
AU - Skelly, Michael J.
AU - Yamamoto, Yoshiharu Y.
AU - Kinoshita, Toshinori
AU - Mori, Izumi C.
AU - Suzuki, Takamasa
AU - Betsuyaku, Shigeyuki
AU - Spoel, Steven H.
AU - Toyota, Masatsugu
AU - Tada, Yasuomi
N1 - Funding Information:
We thank M.F. Thomashow for the seeds of CAMTA3 variants, S. Ishiguro for the seeds of cer1-1 and cer3-1, Y. Takano for Alternaria brassicicola Ryo-1, N. Nakayama, T. Kawasaki, T. Matsushita, and G. Goshima for discussion of the work. This work was supported by JSPS KAKENHI Grant Numbers JP23120520, JP25120718, and JP18K19334 (to Y.T.), JP15H05955 (to Y.T. and T.K.), and JP19H05363, JP21H00366 (to M.N.) and by Cooperative Research Grant #1707 of the Plant Transgenic Design Initiative (PTraD) by Gene Research Center, Tsukuba-Plant Innovation Research Center, the University of Tsukuba (to Y.T.).
Publisher Copyright:
© 2022, The Author(s).
PY - 2022/12
Y1 - 2022/12
N2 - Perception of pathogen-derived ligands by corresponding host receptors is a pivotal strategy in eukaryotic innate immunity. In plants, this is complemented by circadian anticipation of infection timing, promoting basal resistance even in the absence of pathogen threat. Here, we report that trichomes, hair-like structures on the epidermis, directly sense external mechanical forces, including raindrops, to anticipate pathogen infections in Arabidopsis thaliana. Exposure of leaf surfaces to mechanical stimuli initiates the concentric propagation of intercellular calcium waves away from trichomes to induce defence-related genes. Propagating calcium waves enable effective immunity against pathogenic microbes through the CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 3 (CAMTA3) and mitogen-activated protein kinases. We propose an early layer of plant immunity in which trichomes function as mechanosensory cells that detect potential risks.
AB - Perception of pathogen-derived ligands by corresponding host receptors is a pivotal strategy in eukaryotic innate immunity. In plants, this is complemented by circadian anticipation of infection timing, promoting basal resistance even in the absence of pathogen threat. Here, we report that trichomes, hair-like structures on the epidermis, directly sense external mechanical forces, including raindrops, to anticipate pathogen infections in Arabidopsis thaliana. Exposure of leaf surfaces to mechanical stimuli initiates the concentric propagation of intercellular calcium waves away from trichomes to induce defence-related genes. Propagating calcium waves enable effective immunity against pathogenic microbes through the CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 3 (CAMTA3) and mitogen-activated protein kinases. We propose an early layer of plant immunity in which trichomes function as mechanosensory cells that detect potential risks.
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U2 - 10.1038/s41467-022-28813-8
DO - 10.1038/s41467-022-28813-8
M3 - Article
C2 - 35260555
AN - SCOPUS:85126076795
SN - 2041-1723
VL - 13
JO - Nature Communications
JF - Nature Communications
IS - 1
M1 - 1216
ER -