Membranous nephropathy with acquired factor v inhibitor: A case report

Shinji Kitamura, Mahito Misawa, Sayaka Namba, Kenji Tsuji, Rikako Torigoe, Midori Shima, Hirofumi Makino

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Background: Membranous nephropathy is one of the most common causes of nephrotic syndrome in adults. In contrast, acquired factor V inhibitor is a rare bleeding disorder. Case presentation. A 62-year-old Asian man with a history of cerebral hemorrhage, purpura, eosinophilia and hyper immunoglobulin E syndrome developed proteinuria. The bleeding disorder was diagnosed with acquired factor V inhibitors. A renal biopsy revealed that he suffered from membranous nephropathy with glomerular endothelial damage which is reported to be involved in another factor disorder. After the steroid administration, the coagulation test and proteinuria were improved. Conclusions: The presence of factor V inhibitors may have been involved in the development of membranous nephropathy.

Original languageEnglish
Article number553
JournalBMC Research Notes
Issue number1
Publication statusPublished - Dec 21 2013

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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