Metachromins L-Q, new sesquiterpenoid quinones with an amino acid residue from sponge Spongia sp.

Yohei Takahashi; Takaaki Kubota; Jane Fromont; Jun'ichi Kobayashi

doi:10.1016/j.tet.2007.06.031

Metachromins L-Q, new sesquiterpenoid quinones with an amino acid residue from sponge Spongia sp.

Yohei Takahashi, Takaaki Kubota, Jane Fromont, Jun'ichi Kobayashi

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

Six new sesquiterpenoid quinones with an amino acid residue, metachromins L-Q (1-6), have been isolated from an Okinawan marine sponge Spongia sp. The structures and stereochemistry of 1-6 were elucidated on the basis of the spectroscopic data and chemical correlations. Metachromins L (1) and M (2) showed modest cytotoxicity.

Original language	English
Pages (from-to)	8770-8773
Number of pages	4
Journal	Tetrahedron
Volume	63
Issue number	36
DOIs	https://doi.org/10.1016/j.tet.2007.06.031
Publication status	Published - Sept 3 2007
Externally published	Yes

Keywords

Metachromins L-Q
Sesquiterpenoid quinones
Sponge
Spongia sp

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.tet.2007.06.031

Cite this

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title = "Metachromins L-Q, new sesquiterpenoid quinones with an amino acid residue from sponge Spongia sp.",

abstract = "Six new sesquiterpenoid quinones with an amino acid residue, metachromins L-Q (1-6), have been isolated from an Okinawan marine sponge Spongia sp. The structures and stereochemistry of 1-6 were elucidated on the basis of the spectroscopic data and chemical correlations. Metachromins L (1) and M (2) showed modest cytotoxicity.",

keywords = "Metachromins L-Q, Sesquiterpenoid quinones, Sponge, Spongia sp",

author = "Yohei Takahashi and Takaaki Kubota and Jane Fromont and Jun'ichi Kobayashi",

note = "Funding Information: We thank Ms. S. Oka, Center for Instrumental Analysis, Hokkaido University, for FABMS measurements and Mr. Z. Nagahama and Mr. S. Furugen for their help with collection of the sponge. This work was partly supported by a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science, and Technology of Japan.",

year = "2007",

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doi = "10.1016/j.tet.2007.06.031",

language = "English",

volume = "63",

pages = "8770--8773",

journal = "Tetrahedron",

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T1 - Metachromins L-Q, new sesquiterpenoid quinones with an amino acid residue from sponge Spongia sp.

AU - Takahashi, Yohei

AU - Kubota, Takaaki

AU - Fromont, Jane

AU - Kobayashi, Jun'ichi

N1 - Funding Information: We thank Ms. S. Oka, Center for Instrumental Analysis, Hokkaido University, for FABMS measurements and Mr. Z. Nagahama and Mr. S. Furugen for their help with collection of the sponge. This work was partly supported by a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science, and Technology of Japan.

PY - 2007/9/3

Y1 - 2007/9/3

N2 - Six new sesquiterpenoid quinones with an amino acid residue, metachromins L-Q (1-6), have been isolated from an Okinawan marine sponge Spongia sp. The structures and stereochemistry of 1-6 were elucidated on the basis of the spectroscopic data and chemical correlations. Metachromins L (1) and M (2) showed modest cytotoxicity.

AB - Six new sesquiterpenoid quinones with an amino acid residue, metachromins L-Q (1-6), have been isolated from an Okinawan marine sponge Spongia sp. The structures and stereochemistry of 1-6 were elucidated on the basis of the spectroscopic data and chemical correlations. Metachromins L (1) and M (2) showed modest cytotoxicity.

KW - Metachromins L-Q

KW - Sesquiterpenoid quinones

KW - Sponge

KW - Spongia sp

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DO - 10.1016/j.tet.2007.06.031

M3 - Article

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SN - 0040-4020

VL - 63

SP - 8770

EP - 8773

JO - Tetrahedron

JF - Tetrahedron

IS - 36

ER -

Metachromins L-Q, new sesquiterpenoid quinones with an amino acid residue from sponge Spongia sp.

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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