Metachromins R-T, new sesquiterpenoids from marine sponge Spongia sp.

Yohei Takahashi, Mika Yamada, Takaaki Kubota, Jane Fromont, Jun'ichi Kobayashi

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)


Three new sesquiterpenoids, metachromins R-T (1-3), have been isolated from an Okinawan marine sponge Spongia sp. The structures and stereochemistry of 1-3 were elucidated on the basis of the spectroscopic data. Metachromins S (2) and T (3) showed modest cytotoxicity.

Original languageEnglish
Pages (from-to)1731-1733
Number of pages3
JournalChemical and Pharmaceutical Bulletin
Issue number12
Publication statusPublished - Dec 2007
Externally publishedYes


  • Metachromin R
  • Metachromin S
  • Metachromin T
  • Sesquiterpenoid
  • Sponge
  • Spongia sp.

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery


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