Microbial hydrolysis of diketopiperazines: Different types of diketopiperazine-assimilating bacteria

Hiroshi Kanzaki; Shuji Oda; Akio Kobayashi; Kazuyoshi Kawazu

doi:10.1016/S0922-338X(97)80147-X

Microbial hydrolysis of diketopiperazines: Different types of diketopiperazine-assimilating bacteria

Hiroshi Kanzaki
, Shuji Oda
, Akio Kobayashi
, Kazuyoshi Kawazu

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Arthrobacter sp. 1-3-1 and a coryneform rod bacterium, strain T-1-3-Y, which assimilate cyclo(Gly-Gly) and cyclo(Gly-L-Tyr) at high rates, respectively, were isolated from soil. Both bacteria exhibit diketopiperazine-hydrolyzing activity intracellularly in contrast to the extracellular cyclo(Gly-Gly) hydrolase reported previously. Arthrobacter sp. 1-3-1 shows a much broader substrate specificity than strain T-1-3-Y, indicating the diversity of diketopiperazine hydrolysis in nature.

Original language	English
Pages (from-to)	386-388
Number of pages	3
Journal	Journal of Fermentation and Bioengineering
Volume	83
Issue number	4
DOIs	https://doi.org/10.1016/S0922-338X(97)80147-X
Publication status	Published - 1997

Keywords

Cyclo(Gly-Gly)
Cyclo(Gly-L-Tyr)
Enrichment culture
Glycine anhydride

ASJC Scopus subject areas

Biotechnology
Applied Microbiology and Biotechnology

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10.1016/S0922-338X(97)80147-X

Cite this

@article{a29453166d6b414aa7552fd3846082cc,

title = "Microbial hydrolysis of diketopiperazines: Different types of diketopiperazine-assimilating bacteria",

abstract = "Arthrobacter sp. 1-3-1 and a coryneform rod bacterium, strain T-1-3-Y, which assimilate cyclo(Gly-Gly) and cyclo(Gly-L-Tyr) at high rates, respectively, were isolated from soil. Both bacteria exhibit diketopiperazine-hydrolyzing activity intracellularly in contrast to the extracellular cyclo(Gly-Gly) hydrolase reported previously. Arthrobacter sp. 1-3-1 shows a much broader substrate specificity than strain T-1-3-Y, indicating the diversity of diketopiperazine hydrolysis in nature.",

keywords = "Cyclo(Gly-Gly), Cyclo(Gly-L-Tyr), Enrichment culture, Glycine anhydride",

author = "Hiroshi Kanzaki and Shuji Oda and Akio Kobayashi and Kazuyoshi Kawazu",

note = "Funding Information: This work was supported in part by a Grant-in-Aid for Scientific Research from the Ministry of Education, Science, Sports and Culture to HK. We are grateful to the SC-NMR laboratory of Okayama University and the MS laboratory of the Faculty of Agriculture, Okayama University for assistance in the {\textquoteleft}H-NMR and MS experiments, respectively.",

year = "1997",

doi = "10.1016/S0922-338X(97)80147-X",

language = "English",

volume = "83",

pages = "386--388",

journal = "Journal of Fermentation and Bioengineering",

issn = "0922-338X",

publisher = "The Society of Bioscience and Bioengineering Japan/Seibutsu Kogakkai",

number = "4",

}

TY - JOUR

T1 - Microbial hydrolysis of diketopiperazines

T2 - Different types of diketopiperazine-assimilating bacteria

AU - Kanzaki, Hiroshi

AU - Oda, Shuji

AU - Kobayashi, Akio

AU - Kawazu, Kazuyoshi

N1 - Funding Information: This work was supported in part by a Grant-in-Aid for Scientific Research from the Ministry of Education, Science, Sports and Culture to HK. We are grateful to the SC-NMR laboratory of Okayama University and the MS laboratory of the Faculty of Agriculture, Okayama University for assistance in the ‘H-NMR and MS experiments, respectively.

PY - 1997

Y1 - 1997

N2 - Arthrobacter sp. 1-3-1 and a coryneform rod bacterium, strain T-1-3-Y, which assimilate cyclo(Gly-Gly) and cyclo(Gly-L-Tyr) at high rates, respectively, were isolated from soil. Both bacteria exhibit diketopiperazine-hydrolyzing activity intracellularly in contrast to the extracellular cyclo(Gly-Gly) hydrolase reported previously. Arthrobacter sp. 1-3-1 shows a much broader substrate specificity than strain T-1-3-Y, indicating the diversity of diketopiperazine hydrolysis in nature.

AB - Arthrobacter sp. 1-3-1 and a coryneform rod bacterium, strain T-1-3-Y, which assimilate cyclo(Gly-Gly) and cyclo(Gly-L-Tyr) at high rates, respectively, were isolated from soil. Both bacteria exhibit diketopiperazine-hydrolyzing activity intracellularly in contrast to the extracellular cyclo(Gly-Gly) hydrolase reported previously. Arthrobacter sp. 1-3-1 shows a much broader substrate specificity than strain T-1-3-Y, indicating the diversity of diketopiperazine hydrolysis in nature.

KW - Cyclo(Gly-Gly)

KW - Cyclo(Gly-L-Tyr)

KW - Enrichment culture

KW - Glycine anhydride

UR - https://www.scopus.com/pages/publications/0030954080

UR - https://www.scopus.com/pages/publications/0030954080#tab=citedBy

U2 - 10.1016/S0922-338X(97)80147-X

DO - 10.1016/S0922-338X(97)80147-X

M3 - Article

AN - SCOPUS:0030954080

SN - 0922-338X

VL - 83

SP - 386

EP - 388

JO - Journal of Fermentation and Bioengineering

JF - Journal of Fermentation and Bioengineering

IS - 4

ER -

Microbial hydrolysis of diketopiperazines: Different types of diketopiperazine-assimilating bacteria

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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