Mitral valve repair in a patient with myelodysplastic syndrome

Tadashi Omoto, Masanori Hirota, Noboru Ishikawa, Takeo Tedoriya

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Open heart operations for patients with myelodysplastic syndrome (MDS) are associated with infective and bleeding complications. We report a 67-year-old woman with rheumatic, severe mitral regurgitation and mitral stenosis associated with MDS who underwent a mitral valve (MV) repair. Commissurotomy was performed in the anterior commissure. Autologous pericardial patch treated with glutaraldehyde solution was prepared. The anterior leaflet was completely detached from the posterior to the anterior commissure. The anterior leaflet was augmented by autologous pericardial patch treated with glutaraldehyde solution and three pairs of artificial chordae were implanted. Postoperative transesophageal echocardiography showed an increase in the MV orifice and less than trivial mitral regurgitation. Two years after the operation, the patient has normal sinus rhythm with no deterioration of the MV lesion by transthoracic echocardiography. Although the feasibility of MV repair is low in patients with restrictive pathology due to rheumatic disease, MV repair may be preferred in patients with MDS.

Original languageEnglish
Pages (from-to)614-617
Number of pages4
JournalAnnals of Thoracic and Cardiovascular Surgery
Issue number6
Publication statusPublished - 2011
Externally publishedYes


  • Mitral valve repair
  • Myelodysplastic syndrome
  • Rheumatic disease

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine
  • Gastroenterology


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