Modeling complex current waves of a sural nerve after electric stimulation in case of a thin myelin sheath

Takehito Hayami, Keiji Iramina, Xian Chen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A nerve conduction test checks whether the function of a nerve to conduct action potentials is normal or not by measuring compound action potential on the skin. In some neuropathies, a decrease in the thickness of the myelin sheath is observed. This is considered to be a cause of any delay or decay of the conduction of compound action potentials. However degenerated nerves include those with missing nerve fibers, which also decreases the velocity and amplitude of the potential. To investigate the effect of myelin sheath exfoliation, the compound action current was defined as modeling the source of compound action potentials, which are constructed as a complex of axonal currents of each nerve fiber inside a nerve. As a result, the thickness of the nerve fiber contributed to slowing the velocity of the current wave; however, the amplitude of the wave did not always decrease.

Original languageEnglish
Title of host publication2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007
Pages1851-1855
Number of pages5
DOIs
Publication statusPublished - Dec 1 2007
Externally publishedYes
Event2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007 - Beijing, China
Duration: May 23 2007May 27 2007

Publication series

Name2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007

Other

Other2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007
Country/TerritoryChina
CityBeijing
Period5/23/075/27/07

ASJC Scopus subject areas

  • Biomedical Engineering
  • Medicine(all)

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