Molecular evolution of yeast thiolase isozymes

Naoki Kanayama; Mitsuyoshi Ueda; Haruyuki Atomi; Tatsuo Kurihara; Atsuo Tanaka

doi:10.1016/0922-338X(94)90357-3

Molecular evolution of yeast thiolase isozymes

Naoki Kanayama, Mitsuyoshi Ueda, Haruyuki Atomi, Tatsuo Kurihara, Atsuo Tanaka

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

The coexistence of two thiolase isozymes (acetoacetyl-CoA thiolase and 3-ketoacyl-CoA thiolase), essential for the complete degradation of fatty acids, only in peroxisomes of an n-alkane-utilizing yeast Candida tropicalis (Kurihara et al., J. Biochem., 106, 474-478, 1989) is unique in eukaryotic cells. As one of the methods of analysis of molecular information from these isozymes, the calculation of the evolutional distance among thiolases from various organisms suggested that yeast peroxisomal thiolase isozymes are important enzymes in examining the molecular evolution of the fatty acid metabolic pathway and the biogenesis of peroxisomes.

Original language	English
Pages (from-to)	279-282
Number of pages	4
Journal	Journal of Fermentation and Bioengineering
Volume	78
Issue number	4
DOIs	https://doi.org/10.1016/0922-338X(94)90357-3
Publication status	Published - 1994
Externally published	Yes

ASJC Scopus subject areas

Biotechnology
Applied Microbiology and Biotechnology

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title = "Molecular evolution of yeast thiolase isozymes",

abstract = "The coexistence of two thiolase isozymes (acetoacetyl-CoA thiolase and 3-ketoacyl-CoA thiolase), essential for the complete degradation of fatty acids, only in peroxisomes of an n-alkane-utilizing yeast Candida tropicalis (Kurihara et al., J. Biochem., 106, 474-478, 1989) is unique in eukaryotic cells. As one of the methods of analysis of molecular information from these isozymes, the calculation of the evolutional distance among thiolases from various organisms suggested that yeast peroxisomal thiolase isozymes are important enzymes in examining the molecular evolution of the fatty acid metabolic pathway and the biogenesis of peroxisomes.",

author = "Naoki Kanayama and Mitsuyoshi Ueda and Haruyuki Atomi and Tatsuo Kurihara and Atsuo Tanaka",

year = "1994",

doi = "10.1016/0922-338X(94)90357-3",

language = "English",

volume = "78",

pages = "279--282",

journal = "Journal of Fermentation and Bioengineering",

issn = "0922-338X",

publisher = "The Society for Biotechnology, Japan",

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TY - JOUR

T1 - Molecular evolution of yeast thiolase isozymes

AU - Kanayama, Naoki

AU - Ueda, Mitsuyoshi

AU - Atomi, Haruyuki

AU - Kurihara, Tatsuo

AU - Tanaka, Atsuo

PY - 1994

Y1 - 1994

N2 - The coexistence of two thiolase isozymes (acetoacetyl-CoA thiolase and 3-ketoacyl-CoA thiolase), essential for the complete degradation of fatty acids, only in peroxisomes of an n-alkane-utilizing yeast Candida tropicalis (Kurihara et al., J. Biochem., 106, 474-478, 1989) is unique in eukaryotic cells. As one of the methods of analysis of molecular information from these isozymes, the calculation of the evolutional distance among thiolases from various organisms suggested that yeast peroxisomal thiolase isozymes are important enzymes in examining the molecular evolution of the fatty acid metabolic pathway and the biogenesis of peroxisomes.

AB - The coexistence of two thiolase isozymes (acetoacetyl-CoA thiolase and 3-ketoacyl-CoA thiolase), essential for the complete degradation of fatty acids, only in peroxisomes of an n-alkane-utilizing yeast Candida tropicalis (Kurihara et al., J. Biochem., 106, 474-478, 1989) is unique in eukaryotic cells. As one of the methods of analysis of molecular information from these isozymes, the calculation of the evolutional distance among thiolases from various organisms suggested that yeast peroxisomal thiolase isozymes are important enzymes in examining the molecular evolution of the fatty acid metabolic pathway and the biogenesis of peroxisomes.

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U2 - 10.1016/0922-338X(94)90357-3

DO - 10.1016/0922-338X(94)90357-3

M3 - Article

AN - SCOPUS:0027999465

SN - 0922-338X

VL - 78

SP - 279

EP - 282

JO - Journal of Fermentation and Bioengineering

JF - Journal of Fermentation and Bioengineering

IS - 4

ER -

Molecular evolution of yeast thiolase isozymes

Abstract

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