Molecular structure of the Japanese hepatitis C viral genome

Nobuyuki Kato; Makoto Hijikata; Mosanori Nakagawa; Yuko Ootsuyama; Kanae Muraiso; Showgo Ohkoshi; Kunitada Shimotohno

doi:10.1016/0014-5793(91)80322-T

Molecular structure of the Japanese hepatitis C viral genome

Nobuyuki Kato, Makoto Hijikata, Mosanori Nakagawa, Yuko Ootsuyama, Kanae Muraiso, Showgo Ohkoshi, Kunitada Shimotohno

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

The amino acid sequence of the polyprotein deduced from the nucleotide sequence of the Japanese hepatitis C virus genome (N. Kato et. al. (1990) Proc. Natl. Acad. Sci. USA 87, 9524-9528)indicated that this virus is a member of a new class of positive-stranded RNA viruses. Several domains of this polyprotein also showed weak homology with those of flaviviruses and pestiviruses including the chymotrypsin-like serine proteinase. NTPase and RNA-dependent RNA polymerase.

Original language	English
Pages (from-to)	325-328
Number of pages	4
Journal	FEBS Letters
Volume	280
Issue number	2
DOIs	https://doi.org/10.1016/0014-5793(91)80322-T
Publication status	Published - Mar 25 1991
Externally published	Yes

Keywords

Amino acid sequence.
HCV-J
Non-A, non-B hepatitis
RNA virus

ASJC Scopus subject areas

Biophysics
Structural Biology
Biochemistry
Molecular Biology
Genetics
Cell Biology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/0014-5793(91)80322-T

Cite this

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title = "Molecular structure of the Japanese hepatitis C viral genome",

abstract = "The amino acid sequence of the polyprotein deduced from the nucleotide sequence of the Japanese hepatitis C virus genome (N. Kato et. al. (1990) Proc. Natl. Acad. Sci. USA 87, 9524-9528)indicated that this virus is a member of a new class of positive-stranded RNA viruses. Several domains of this polyprotein also showed weak homology with those of flaviviruses and pestiviruses including the chymotrypsin-like serine proteinase. NTPase and RNA-dependent RNA polymerase.",

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T1 - Molecular structure of the Japanese hepatitis C viral genome

AU - Kato, Nobuyuki

AU - Hijikata, Makoto

AU - Nakagawa, Mosanori

AU - Ootsuyama, Yuko

AU - Muraiso, Kanae

AU - Ohkoshi, Showgo

AU - Shimotohno, Kunitada

PY - 1991/3/25

Y1 - 1991/3/25

N2 - The amino acid sequence of the polyprotein deduced from the nucleotide sequence of the Japanese hepatitis C virus genome (N. Kato et. al. (1990) Proc. Natl. Acad. Sci. USA 87, 9524-9528)indicated that this virus is a member of a new class of positive-stranded RNA viruses. Several domains of this polyprotein also showed weak homology with those of flaviviruses and pestiviruses including the chymotrypsin-like serine proteinase. NTPase and RNA-dependent RNA polymerase.

AB - The amino acid sequence of the polyprotein deduced from the nucleotide sequence of the Japanese hepatitis C virus genome (N. Kato et. al. (1990) Proc. Natl. Acad. Sci. USA 87, 9524-9528)indicated that this virus is a member of a new class of positive-stranded RNA viruses. Several domains of this polyprotein also showed weak homology with those of flaviviruses and pestiviruses including the chymotrypsin-like serine proteinase. NTPase and RNA-dependent RNA polymerase.

KW - Amino acid sequence.

KW - HCV-J

KW - Non-A, non-B hepatitis

KW - RNA virus

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ER -

Molecular structure of the Japanese hepatitis C viral genome

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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