TY - JOUR
T1 - MULTIPLE CARCINOID TUMOR COMBINED WITH MUCOSAL CARCINOMA IN THE STOMACH
T2 - A Case Report
AU - Yoshino, Tadashi
AU - Ohtsuki, Yuji
AU - Shimada, Yoshiaki
AU - Takahashi, Kiyoshi
AU - Sonobe, Hiroshi
AU - Hayashi, Kazuhiko
AU - Nakamura, Shinichi
AU - Motoi, Makoto
AU - Akagi, Tadaatsu
PY - 1987/10
Y1 - 1987/10
N2 - A case of gastric multipe carcinoid tumor combined with mucosal carcinoma in a 63‐year‐old female is reported. The carcinoid tumors, larger than 0.5 mm in diameter, and endocrine cell micronests, smaller than 0.5 mm in diameter, were mostly located in areas of chronic atrophic gastritis. Their distribution was coincident with that of multiple carcinoid tumor in type A gastritis. The majority of the tumor cells were positive for human chorionic gonadotropin (HCG) and Leu 7 by immunohistochemistry and contained various numbers of intracytoplasmic secretory granules as revealed by electron microscopy. Two mucosal carcinoma foci did not show endocrine characteristics. These carcinoid tumors were thought to have originated in HCG‐producing argyrophil cells which had been stimulated by hypergastrinemia accompanying chronic atrophic gastritis. The mucosal carcinomas were regarded as incidental.
AB - A case of gastric multipe carcinoid tumor combined with mucosal carcinoma in a 63‐year‐old female is reported. The carcinoid tumors, larger than 0.5 mm in diameter, and endocrine cell micronests, smaller than 0.5 mm in diameter, were mostly located in areas of chronic atrophic gastritis. Their distribution was coincident with that of multiple carcinoid tumor in type A gastritis. The majority of the tumor cells were positive for human chorionic gonadotropin (HCG) and Leu 7 by immunohistochemistry and contained various numbers of intracytoplasmic secretory granules as revealed by electron microscopy. Two mucosal carcinoma foci did not show endocrine characteristics. These carcinoid tumors were thought to have originated in HCG‐producing argyrophil cells which had been stimulated by hypergastrinemia accompanying chronic atrophic gastritis. The mucosal carcinomas were regarded as incidental.
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U2 - 10.1111/j.1440-1827.1987.tb02477.x
DO - 10.1111/j.1440-1827.1987.tb02477.x
M3 - Article
C2 - 3434286
AN - SCOPUS:0023432407
SN - 1320-5463
VL - 37
SP - 1669
EP - 1678
JO - Acta Pathologica Japonica
JF - Acta Pathologica Japonica
IS - 10
ER -