Multiple nuclide imaging in live mouse using semiconductor compton camera for multiple molecular imaging

Shinji Motomura; Yousuke Kanayama; Hiromitsu Haba; Yasuyoshi Watanabe; Shuichi Enomoto

doi:10.1109/NSSMIC.2007.4436935

Multiple nuclide imaging in live mouse using semiconductor compton camera for multiple molecular imaging

Shinji Motomura, Yousuke Kanayama, Hiromitsu Haba, Yasuyoshi Watanabe, Shuichi Enomoto

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

We have demonstrated the concept of multiple molecular imaging by use of semiconductor Compton cameras. The Compton camera used in this work comprises two double-sided orthogonal-strip germanium detectors, and their excellent energy resolution enables discrimination of the nuclides and accurate determination of the scattering angle especially for sub-MeV to MeV-range gamma rays. Three radioactive tracers of ⁶⁵ZnCl₂, ⁸⁵SrCl₂, and iodinated (¹³¹I) methylnorcholestenol were simultaneously measured in the live-mouse imaging experiment. The images of the three tracers were successfully obtained, which showed the different behavior in the living organism.

Original language	English
Title of host publication	2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC
Pages	3741-3742
Number of pages	2
DOIs	https://doi.org/10.1109/NSSMIC.2007.4436935
Publication status	Published - 2007
Externally published	Yes
Event	2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC - Honolulu, HI, United States Duration: Oct 27 2007 → Nov 3 2007

Publication series

Name	IEEE Nuclear Science Symposium Conference Record
Volume	5
ISSN (Print)	1095-7863

Other

Other	2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC
Country/Territory	United States
City	Honolulu, HI
Period	10/27/07 → 11/3/07

ASJC Scopus subject areas

Radiation
Nuclear and High Energy Physics
Radiology Nuclear Medicine and imaging

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10.1109/NSSMIC.2007.4436935

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Motomura, S., Kanayama, Y., Haba, H., Watanabe, Y., & Enomoto, S. (2007). Multiple nuclide imaging in live mouse using semiconductor compton camera for multiple molecular imaging. In 2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC (pp. 3741-3742). Article 4436935 (IEEE Nuclear Science Symposium Conference Record; Vol. 5). https://doi.org/10.1109/NSSMIC.2007.4436935

Multiple nuclide imaging in live mouse using semiconductor compton camera for multiple molecular imaging. / Motomura, Shinji; Kanayama, Yousuke; Haba, Hiromitsu et al.
2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC. 2007. p. 3741-3742 4436935 (IEEE Nuclear Science Symposium Conference Record; Vol. 5).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Motomura, S, Kanayama, Y, Haba, H, Watanabe, Y & Enomoto, S 2007, Multiple nuclide imaging in live mouse using semiconductor compton camera for multiple molecular imaging. in 2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC., 4436935, IEEE Nuclear Science Symposium Conference Record, vol. 5, pp. 3741-3742, 2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC, Honolulu, HI, United States, 10/27/07. https://doi.org/10.1109/NSSMIC.2007.4436935

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abstract = "We have demonstrated the concept of multiple molecular imaging by use of semiconductor Compton cameras. The Compton camera used in this work comprises two double-sided orthogonal-strip germanium detectors, and their excellent energy resolution enables discrimination of the nuclides and accurate determination of the scattering angle especially for sub-MeV to MeV-range gamma rays. Three radioactive tracers of 65ZnCl2, 85SrCl2, and iodinated (131I) methylnorcholestenol were simultaneously measured in the live-mouse imaging experiment. The images of the three tracers were successfully obtained, which showed the different behavior in the living organism.",

author = "Shinji Motomura and Yousuke Kanayama and Hiromitsu Haba and Yasuyoshi Watanabe and Shuichi Enomoto",

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AB - We have demonstrated the concept of multiple molecular imaging by use of semiconductor Compton cameras. The Compton camera used in this work comprises two double-sided orthogonal-strip germanium detectors, and their excellent energy resolution enables discrimination of the nuclides and accurate determination of the scattering angle especially for sub-MeV to MeV-range gamma rays. Three radioactive tracers of 65ZnCl2, 85SrCl2, and iodinated (131I) methylnorcholestenol were simultaneously measured in the live-mouse imaging experiment. The images of the three tracers were successfully obtained, which showed the different behavior in the living organism.

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Multiple nuclide imaging in live mouse using semiconductor compton camera for multiple molecular imaging

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