TY - GEN
T1 - Multisensory integration of peripherally presented audiovisual stimuli in older adults
T2 - 2012 9th IEEE International Conference on Mechatronics and Automation, ICMA 2012
AU - Yang, Weiping
AU - Gao, Yulin
AU - Yang, Jingjing
AU - Takahashi, Satoshi
AU - Kimura, Takahiro
AU - Wu, Jinglong
PY - 2012
Y1 - 2012
N2 - Alzheimer's disease (AD) is the most common form of dementia among older people. The number of dementia is increasing rapidly with appearing phenomenon of aging. A previous study showed that brain glucose metabolism was different with that between healthy people and Alzheimer patients during the response to passive audiovisual stimulation. In the present study, we designed a discrimination task that unimodal visual stimuli, unimodal auditory stimuli and bimodal audiovisual stimuli were randomly presented left or right side of screen and investigated the multisensory integration of peripherally presented audiovisual stimuli in older adults using Event-Related Potential. Two periods of significant interactions were found: the right occipital area at 160-200 ms after the presentation of the stimulus and the left fronto-central area at 300-600 ms after the presentation of the stimulus. Our results identified multisensory integration brain activities in the healthy older adults. In next study, we will discuss audiovisual integration for patients with Alzheimer's disease using experiment design of this study, and hope to find out an excellent method for Alzheimer's disease early detection.
AB - Alzheimer's disease (AD) is the most common form of dementia among older people. The number of dementia is increasing rapidly with appearing phenomenon of aging. A previous study showed that brain glucose metabolism was different with that between healthy people and Alzheimer patients during the response to passive audiovisual stimulation. In the present study, we designed a discrimination task that unimodal visual stimuli, unimodal auditory stimuli and bimodal audiovisual stimuli were randomly presented left or right side of screen and investigated the multisensory integration of peripherally presented audiovisual stimuli in older adults using Event-Related Potential. Two periods of significant interactions were found: the right occipital area at 160-200 ms after the presentation of the stimulus and the left fronto-central area at 300-600 ms after the presentation of the stimulus. Our results identified multisensory integration brain activities in the healthy older adults. In next study, we will discuss audiovisual integration for patients with Alzheimer's disease using experiment design of this study, and hope to find out an excellent method for Alzheimer's disease early detection.
KW - ERP
KW - audiovisual integration
KW - older adults
KW - peripherally
UR - http://www.scopus.com/inward/record.url?scp=84867615060&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84867615060&partnerID=8YFLogxK
U2 - 10.1109/ICMA.2012.6283169
DO - 10.1109/ICMA.2012.6283169
M3 - Conference contribution
AN - SCOPUS:84867615060
SN - 9781467312776
T3 - 2012 IEEE International Conference on Mechatronics and Automation, ICMA 2012
SP - 563
EP - 568
BT - 2012 IEEE International Conference on Mechatronics and Automation, ICMA 2012
Y2 - 5 August 2012 through 8 August 2012
ER -